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[会议论文] 作者：Herbert Waldmann,
来源：The 24th International Society of Heterocyclic Chemistry Con 年份：2013
Relevance to nature is one of the most important criteria to be met by compound classes for chemical biology and medicinal chemistry research.The underlying fra...
[会议论文] 作者：陈永湘,Shehab A.Ismail,Alfred Wittinghofer,Herbert Waldmann,
来源：中国化学会第28届学术年会 年份：2012
Rheb和K-Ras4B同为小GTP 酶,分别在mTOR和MAPK两个重要的细胞信号通路中起着关键的分子开关作用。[1,2] 这两个蛋白的C-末端能被法尼基(又名三异戊二烯基,属脂基类)和甲基修饰,这是它们正确分布在细胞膜从而发挥调控功能的必要条件。但由于仅利用生物手段,很难......
Modulating effects of acyl-CoA synthetase 5-derived mitochondrial Wnt2B palmitoylation on intestinal
[期刊论文] 作者：Christina Klaus,Ursula Schneider,Christian Hedberg,Anke K Schütz,Jürgen Bernhagen,Herbert Waldmann,Nikolaus,
来源：World Journal of Gastroenterology 年份：2014
AIM:To investigate the role of acyl-CoA synthetase 5(ACSL5)activity in Wnt signaling in intestinal surface epithelia.METHODS:Several cell lines were used to inv...
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