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[期刊论文] 作者：Huile Gao,,
来源：Acta Pharmaceutica Sinica B 年份：2016
Due to the ability of the blood–brain barrier(BBB) to prevent the entry of drugs into the brain, it is a challenge to treat central nervous system disorders ph...
The application of nitric oxide delivery in nanoparticle-based tumor targeting drug delivery and tre
[期刊论文] 作者：Lin Qin,Huile Gao,
来源：亚洲药物制剂科学(英文) 年份：2019
Nitric oxide(NO) shows great role in tumor biology. Recent years, more and more researches utilized NO donor in tumor targeting drug delivery and treatment. In...
[期刊论文] 作者：Chuan Hu,Huile Gao,
来源：亚洲药物制剂科学(英文) 年份：2021
Immunotherapy of tumor attracts great attention in the past several years attributing to the potential of completely erasing primary tumor and metastasis.Theref...
Incorporation of lapatinib into lipoprotein-like nanoparticles improves both the solubility and anti
[会议论文] 作者：Huile Gao,Xinguo Jiang,
来源：2012年中国药物制剂大会——中国药学会药剂专业委员会年会、亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 年份：2012
...
Bilirubin-based copolymers self-assembled micelles with shape changeable ability and tumor targeting
[会议论文] 作者：Rui Liu,Huile Gao,
来源：第三届国际纳米药物大会 ChinaNanomedicine 2018 The 3rd International Con 年份：2018
Herein,we reported a shape-changeable micelle composed of two kinds of triblock copolymers,BR-FFVLK-PEG and Ce6-FFVLK-PEG,which both included(i)functional hydrophobic block(bilirubin,BR or chlorin e6,...
Legumain-responsive aggregation of gold nanoparticles for enhanced retention in tumor via click cycl
[会议论文] 作者：Shaobo Ruan,Huile Gao,
来源：中国毒理学会纳米毒理学专业委员会第五届全国纳米生物效应与毒理学会议暨中国纳米医学会议2016(China Nanomed 年份：2016
...
[期刊论文] 作者：Zhijian Luo,Yan Dai,Huile Gao,
来源：药学学报（英文版） 年份：2019
Hyaluronic acid (HA) is a natural polysaccharide that has gained much attention due to its biocompatibility,enzyme degradation capacity and active tumor targeti...
[期刊论文] 作者：Huile Gao,Zhiqing Pang,Wei He,
来源：药学学报（英文版） 年份：2020
Drug delivery to treat cancer has attracted considerably and increasingly high attention.Several drug delivery systems are available in the market and many othe...
Matrix metalloprotease triggered size-shrinkable gelatin-gold nanoparticles for tumor microenvironme
[会议论文] 作者：Shaobo Ruan,Qin He,Huile Gao,
来源：2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 年份：2015
Nanomedicines are appealing increasing attention because of their excellent performances, such as flexibility, biocompatibility and selectivity, which make...
PTX-loaded Liposomes modified by a pH-responsive cell penetrating peptide with the ability of active
[会议论文] 作者：Kairong Shi,Huile Gao,Qin He,
来源：The 6th International Conference on Nanoscience and Technolo 年份：2015
Melanoma is a malignant tumor derived from epidermal melanocytes [1].Integrin αvβ3-overexpressed in melanoma tumors plays an important role in tumor growt...
Matrix metalloprotease triggered size-shrinkable gelatin-gold nanoparticles for tumor microenvironme
[会议论文] 作者：Shaobo Ruan,Qin He,Huile Gao,
来源：2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 年份：2015
Nanomedicines are appealing increasing attention because of their excellent performances, such as flexibility, biocompatibility and selectivity, which make the combination of therapy and diagnosis pos...
[会议论文] 作者：Jiantao Chen,Qin He,Huile Gao,
来源：2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 年份：2015
The fluorescent carbonaceous nanodots (CDs) were suitable for biomedical applications owing to their excellent photoluminescent properties.However, their toxicity has not been evaluated sufficiently.I...
Tumor microenvironment sensitive doxorubicin delivery and release to glioma using angiopep-2 decorat
[会议论文] 作者：Shaobo Ruan,Qin He,Huile Gao,
来源：2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 年份：2014
Glioma, the most aggressive and common intracranialtumor, is considered as the major cause of death from central nervous systems (CNS).Although various methods have been explored to conquer it, includ...
Non-invasive in vivo diagnosis of brain glioma using RGD decorated fluorescent carbonaceous nanosphe
[会议论文] 作者：Shaobo Ruan,Qin He,Huile Gao,
来源：2014年中国药学大会暨第十四届中国药师周 年份：2014
Carbon nanomaterials,including graphene,carbon nanotubes,fullerene and fluorescent carbonaceous nanospheres (CDs),have been extensively applied in many fields.Among which,CDs have generated much excit...
dual strategy to improve the penetration and treatment of breast cancer by combining shrinking nanop
[会议论文] 作者：Xingli Cun,Qin He,Huile Gao,
来源：2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 年份：2016
...
PTX-loaded Liposomes modified by a pH-responsive cell penetrating peptide with the ability of active
[会议论文] 作者：Kairong Shi,Huile Gao,Qin He,
来源：The 6th International Conference on Nanoscience and Technolo 年份：2015
Melanoma is a malignant tumor derived from epidermal melanocytes [1].Integrin αvβ3-overexpressed in melanoma tumors plays an important role in tumor growth and may serve as a potential target for nano...
A high performance deep tumor penetration nanocarrier via overcoming both tumor extracellular matrix
[会议论文] 作者：Yang Wang,Huile Gao,Qin He,
来源：The 6th International Conference on Nanoscience and Technolo 年份：2015
The physiological barriers of tumor itself are main challenges that blunt the non-surgical treatment of malignant solid tumors [1,2].The tumor extravascular barrier(TEVB)composed of tumor extracellula...
,Theranostic nanoparticles with tumor-specific enzyme-triggered size reduction and drug release to p
[期刊论文] 作者：Rui Liu,Chuan Hu,Yuanyuan Yang,Jingqing Zhang,Huile Gao,
来源：药学学报（英文版） 年份：2019
Although progress has been indeed made by nanomedicines,their efficacies for cancer treatment remain low,consequently leading to failures in translation to clin...
Losartan increases tumor permeability to promote drug distribution and antitumor efficacy of pH sens
[会议论文] 作者：Li Zhang,Yang Wang,Yuting Yang,Huile Gao,Qin He,
来源：2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 年份：2014
The failure of sufficient accumulation of nanoparticles in tumor tissues is a primary problem to tumor therapy, which was because the extracellular matrix (ECM) produced by tumor and stromal cells and...
[期刊论文] 作者：Wei Zhang,Fei Wang,Chuan Hu,Yang Zhou,Huile Gao,Jiang Hu,
来源：药学学报（英文版） 年份：2020
As one of the most serious threats to human being,cancer is hard to be treated when metas-tasis happens.What's worse,there are few identified targets of metasta...
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