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Screening and verifying potential NTCP inhibitors from herbal medicinal ingredients using the LLC-PK
[期刊论文] 作者：SHEN Zhuo-Wei,LUO Meng-Yue,HU Hai-Hong,ZHOU Hui,JIANG Hui-Di,YU Lu-Shan,ZENG Su,,
来源：Chinese Journal of Natural Medicines 年份：2016
NTCP is specifically expressed on the basolateral membrane of hepatocytes, participating in the enterohepatic circulation of bile salts, especially conjugated b...
Mechanism for ginkgolic acid(15:1)-induced MDCK cell necrosis: Mitochondria and lysosomes damages an
[期刊论文] 作者：YAO Qing-Qing,LIU Zhen-Hua,XU Ming-Cheng,HU Hai-Hong,ZHOU Hui,JIANG Hui-Di,YU Lu-Shan,ZENG Su,,
来源：Chinese Journal of Natural Medicines 年份：2017
Ginkgolic acids(GAs), primarily found in the leaves, nuts, and testa of ginkgo biloba, have been identified with suspected allergenic, genotoxic and cytotoxic p...
Potential role of organic cation transporter 2 in the renal tubular toxicity of nitidine chloride in
[会议论文] 作者：LI Li-ping,YANG Xi,WEN Ya-yun,SONG Fei-feng,LEI Hong-mei,ZHOU Hui,ZENG Su,JIANG Hui-di,
来源：2015年第一届药代动力学朝阳论坛 年份：2015
Nitidine chloride (NC), a benzophenanthridine alkaloid, h as many biological properties, such as anti-inflammatory and anti-cancer.However, its cytotoxicity was also reported.Our previous study demons...
[会议论文] 作者：CHEN Zhong-Jian,DAI Yan-Qing,KONG Si-Si,SONG Fei-Feng,LI Li-Ping,ZHOU Hui,ZENG Su,JIANG Hui-Di,
来源：第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份：2012
Aim Luteolin (3, 4, 5, 7-tetrahydroxyflavone) is a typical flavonoid widely distributed in plants, which possesses many biological effects.Due to its catecholic ring, luteolin could be methylated at m...
Mechanism for ginkgolic acid (15 ∶ 1)-induced MDCK cell necrosis: Mitochondria and lysosomes damages
[期刊论文] 作者：YAO Qing-Qing,LIU Zhen-Hua,XU Ming-Cheng,HU Hai-Hong,ZHOU Hui,JIANG Hui-Di,YU Lu-Shan,ZENG Su,
来源：中国天然药物 年份：2017
Ginkgolic acids (GAs),primarily found in the leaves,nuts,and testa of ginkgo biloba,have been identified with suspected allergenic,genotoxic and cytotoxic properties.However,little information is available about GAs toxicity in kidneys and ......
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