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Nifedipine reduces iron accumulation and dopamine neuron degeneration in the iron-overloaded substan
[会议论文] 作者：Ze-Gang MA,Jun-Xia XIE,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Objective To investigate whether nifedipine, a blocker of L-type calcium channels can prevent iron accumulation and dopamine neuron degeneration in the substantia nigra (SN) of acute and chronic iron-...
[会议论文] 作者：Tian-Wei LIU,Jun-Xia XIE,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
The ideal therapeutic method for Parkinsons disease (PD) should not only replenish the DA content,but also protect the remaining dopaminergic neurons.The combination of the stem cell transplantation a...
Adenoviral Gene Transfer of the growth hormone secretagogue receptor(GHSR)-1a antagonized MPTP-induc
[会议论文] 作者：Hong Jiang,Li Liu,Jun-Xia Xie,
来源：2009国际分子神经退行性疾病大会(2009 International Conference on molecular 年份：2009
...
Adenoviral Gene Transfer of the growth hormone secretagogue receptor(GHSR)-1a antagonized MPTP-induc
[会议论文] 作者：Hong Jiang,Li Liu,Jun-Xia Xie,
来源：2009国际分子神经退行性疾病大会(2009 International Conference on molecular 年份：2009
...
[会议论文] 作者：Bing LUO,Hong JIANG,Jun-Xia XIE,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
Objective DMT 1-Divalent Metal (Ion) Transporter 1 or SLC 11A2/DCT 1/Nramp2-transports Fe2+ into the duodenum and out of the endosome during the transferrin cycle.DMT1 also is important in non-transfe...
Curcumin attenuates 6-hydroxydopamine-induced cytotoxicity by anti-oxidation and nuclear factor-kapp
[会议论文] 作者：Jun Wang,Xi-Xun Du,Hong Jiang,Jun-Xia Xie,
来源：2009国际分子神经退行性疾病大会(2009 International Conference on molecular 年份：2009
...
Protective effects of a polysaccharide from Spirulina platensis on dopaminergic neurons in an MPT-Pi
[期刊论文] 作者：Fang Zhang,Jian Lu,Ji-guo Zhang,Jun-xia Xie,,
来源：Neural Regeneration Research 年份：2015
The present study aimed to determine whether a polysaccharide obtained from Spirulina platensis shows protective effects on dopaminergic neurons. A Parkinson’s...
[会议论文] 作者：Wen-Ting JIA,Hua-Min XU,Hong JIANG,Jun-Xia XIE,
来源：第二届中国国际生物微量元素大会 年份：2014
Elevated iron accumulation and increased divalent metal transporter 1 (DMT1) expression have been reported in the substantia nigra (SN) of Parkinson s dise...
Protective effects of a polysaccharide fromSpirulina platensis on dopaminergic neurons in an MPTP-in
[期刊论文] 作者：Fang Zhang,Jian Lu,Ji-guo Zhang,Jun-xia Xie,
来源：中国神经再生研究（英文版） 年份：2015
The present study aimed to determine whether a polysaccharide obtained fromSpirulina platensis shows protective effects on dopaminergic neurons. A Parkinson’s...
Curcumin attenuates 6-hydroxydopamine-induced cytotoxicity by anti-oxidation and nuclear factor-kapp
[会议论文] 作者：Jun Wang,Xi-Xun Du,Hong Jiang,Jun-Xia Xie,
来源：2009国际分子神经退行性疾病大会(2009 International Conference on molecular 年份：2009
...
Ghrelin protects dopaminergic neurons in the substantia nigra from MPTP-induced neurodegeneration in
[会议论文] 作者：Lin-Jing LI,Hong JIANG,Jun WANG,Jun-Xia XIE,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
The aim of the study was to investigate the anti-apoptotic effect of an endogenous neuropeptide,ghrelin on the mouse MPTP model of PD.Ghrelin,a stomach-derived hormone inducing growth hormone (GH) rel...
Neuroprotective effects of ginsenoside Rg1 on the dopaminergic neuronsin the substantia nigra of MPT
[会议论文] 作者：Hai-Dong YANG,Jun WANG,Hong JIANG,Jun-Xia XIE,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
In the present study,the effects of Ginsenoside Rg1 (Rg1) on 1-methy-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced dopamineregic neuron degeneration in the substantia nigra (SN) of C57BL6 mice we...
Myricetin attenuates MPP+-induced cytotoxicity by anti-oxidation and inhibition of MKK4 and JNK acti
[会议论文] 作者：Kai ZHANG,Ze-Gang MA,Jun WANG,Jun-Xia XIE,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Objective Increasing evidence suggests that oxidative stress may be implicated in the degeneration of dopaminergic neurons in Parkinsons disease (PD), and anti-oxidation has been shown to be effective...
Overexpression of ferroportin1 and/or hephaestin attenuated iron induced oxidative stress in MES23.5
[会议论文] 作者：Ning SONG,Jun WANG,Hong JIANG,Jun-Xia XIE,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
Ferroportin1 (FP1) and hephaestin (HP) are newly-found iron transporters cooperating in the iron effiux process in the gut.While their roles in brain iron homeostasis are not fully elucidated.Our prev...
[会议论文] 作者：Le Qu,Huamin Xu,Hong Jiang,Jun-Xia Xie,
来源：The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份：2015
Rosmarinic acid(RA)is a naturally occurring polyphenolic compound,and is composed of caffeic acid and danshensu....
[会议论文] 作者：Peng Chen,Ning Song,Jun Wang,Jun-Xia Xie,
来源：2016年国际生理学学术大会 年份：2016
The adipocytokine apelin,an endogenous neuropeptide,has been implicated as a key regulator of central and peripheral responses to multiple homeostatic perturbations.Recent evidence suggests that apeli...
[会议论文] 作者：Peng Chen,Ning Song,Hong Jiang,Jun-Xia Xie,
来源：The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份：2015
...
Protection of MES23.5 dopaminergic cells by obestatin is mediated by proliferative rather than anti-
[期刊论文] 作者：Xiao-Li Shen,Feng-Ju Jia,Ning Song,Jun-Xia Xie,Hong Jiang,,
来源：Neuroscience Bulletin 年份：2014
Obestatin is an endogenous peptide sharing a precursor with ghrelin. This study aims to investigate whether and how obestatin protects MES23.5 dopaminergic cell...
Up-regulated divalent metal transporter 1 by 1-Methyl-4-phenyl-pyridinium iodide (MPP+) enhances iro
[会议论文] 作者：Shuzhen ZHANG,Jun WANG,Ning SONG,Hong JIANG,Jun-Xia XIE,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
Based on the previous study,we assume that newly discovered iron transporter,divalent metal transporter 1 (DMT1),might be involved in the MPTP-induced nigral iron accumulation.In the present study,we...
Activation of ATP-sensitive potassium channels enhances DMT1-mediated ferrous iron uptake in SK-N-SH
[会议论文] 作者：Xi-Xun DU,Hua-Min XU,Ning SONG,Hong JIANG,Jun-Xia XIE,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Objective Elevated iron accumulation has been reported in the substantia nigra (SN) in Parkinsons disease (PD).Our previous study observed that increased levels of the iron importer divalent metal tra...
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