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Mitochondrial Targeting of Vitamin E Succinate Enhances its Anti-cancer Activity via Mitochondrial C
[会议论文] 作者：Lanfeng Dong,
来源：BITs 3rd Annual World Cancer Congress-2012(2012第五届世界癌症大会) 年份：2012
Mitochondria are emerging as intriguing targets for anti-cancer agents.Vitamin E succinate (VES) has been shown to efficiently kill different types of cancer cells.A mitochondrially targeted analogue...
[会议论文] 作者：Lanfeng Dong,
来源：2011第四届世界癌症大会 年份：2011
The number of patients diagnosed with neoplastic disease is expected to increase up to three-fold by 2030.Thus, the search for efficient and selective anti-cancer compounds with few side-effects is of...
Mitochondrial Targeting of α-tocopheryl Succinate Enhances its Proapoptotic Efficacy: A New Paradigm
[会议论文] 作者：Lanfeng Dong,
来源：2013第六届世界癌症大会 年份：2013
Mitochondria are emerging as intriguing targets for anti-cancer agents.We tested here a novel approach, whereby the mitochondrially targeted delivery of anti-cancer drugs is enhanced by the addition o...
Cancer Cells with Dysfunctional Mitochondria Restore Their Mitochondrial Function and Tumorigenic Ca
[会议论文] 作者：Lanfeng Dong,AyenachewBezawork-Geleta,Mike Berridge,Jiri Neuzil,
来源：2016第九届世界癌症大会 年份：2016
Mitochondrial DNA (mtDNA) is critically involved in tumorigenesis/metastasis;loss of mtDNA correlates with loss of tumorigenicity of cancer cells and their poor growth....
MicroRNA-126 Suppresses Mesothelioma Malignancy by Targeting IRS1 and Interfering with the Mitochond
[会议论文] 作者：Lanfeng Dong,Lory Santarellib,Jiri Neuzilc,Marco Tomasettib,
来源：2014第七届世界癌症大会 年份：2014
MicroRNA-126 (MiR126) was found to be frequently lost in many types of cancer including malignant mesothelioma (MM), which represents one of the most challenging neoplastic diseases.In this study, we...
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