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Lipidomics reveals carnitine palmitoyltransferase 1C protects cancer cells from lipotoxicity and sen
[期刊论文] 作者：Huizhen Zhang,Yongtao Wang,Lihuan Guan,Yixin Chen,Panpan Chen,Jiahong Sun,Frank J.Gonzalez,Min Huang,,
来源：药物分析学报:英文版 年份：2021
Lipotoxicity, caused by intracellular lipid accumulation, accelerates the degenerative process of cellular senescence, which has implications in cancer development and therapy. Previously, carnitine palmitoyltransferase 1C(CPT1C), a mitocho......
Lipidomics reveals carnitine palrnitoyltransferase 1C protects cancer cells from lipotoxicity and se
[期刊论文] 作者：Huizhen Zhang,Yongtao Wang,Lihuan Guan,Yixin Chen,Panpan Chen,Jiahong Sun,Frank J.Gonzalez,Min Huang,,
来源：药物分析学报（英文版） 年份：2021
Lipotoxicity,caused by intracellular lipid accumulation,accelerates the degenerative process of cellular senescence,which has implications in cancer development...
SIRT6 as a key event linking P53 and NRF2 counteracts APAP-induced hepatotoxicity through inhibiting
[期刊论文] 作者：Zhou,Xiaomei Fan,Tingying Jiao,Wenzhou Li,Panpan Chen,Yiming Jiang,Jiahong Sun,Yixin Chen,Pan Chen,Lihuan Guan,
来源：药学学报（英文版） 年份：2021
Acetaminophen(APAP)overdose is the leading cause of drug-induced liver injury,and its prognosis depends on the balance between hepatocyte death and regeneration...
[会议论文] 作者：Pan Chen,Dongshun Li,Yixin Chen,Jiahong Sun,Kaili Fu,Lihuan Guan,Huizhen Zhang,Yiming Jiang,Xi Li,Xuezhen,
来源：2018第23届广东省药师周大会 年份：2017
BACKGROUND AND PURPOSE: Tumor suppressor p53 is traditionally recognized as a surveillance molecule to preserve genome integrity.Recent studies have emerged on discovering its functions in metabolic d...
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