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Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control
[期刊论文] 作者:Linglong Deng,Hannah Petrek,Mei-Juan Tu,Neelu Batra,Ai-Xi Yu,Ai-Ming Yu,
来源:药学学报(英文版) 年份:2021
With the understanding of microRNA(miRNA or miR)functions in tumor initiation,pro-gression,and metastasis,efforts are underway to develop new miRNA-based therapies.Very recently,we demonstrated effectiveness of a novel humanized bioengineer......
,Bioengineered miR-27b-3p and miR-328-3p modulate drug metabolism and disposition via the regulation
[期刊论文] 作者:Xin Li,Ye Tian,Mei-Juan Tu,Pui Yan Ho,Neelu Batra,Ai-Ming Yu,
来源:药学学报(英文版) 年份:2019
Drug-metabolizing enzymes,transporters,and nuclear receptors are essential for the absorption,distribution,metabolism,and excretion (ADME) of drugs and xenobiot...
,Bioengineered miR-328-3p modulates GLUT1-mediated glucose uptake and metabolism to exert synergisti
[期刊论文] 作者:Wanrong Yi,Mei-Juan Tu,Zhenzhen Liu,Chao Zhang,Neelu Batra,Ai-Xi Yu,Ai-Ming Yu,
来源:药学学报(英文版) 年份:2020
MicroRNAs (miRNAs or miRs) are small noncoding RNAs derived from genome to control target gene expression.Recently we have developed a novel platform permitting...
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