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A combination therapy for KRAS-mutant lung cancer by targeting synthetic lethal partners of mutant K
[期刊论文] 作者:Xiufeng Pang,Mingyao Liu,,
来源:Chinese Journal of Cancer 年份:2016
The KRAS gene is frequently mutated in multiple cancer types,but it fell off the drug discovery radar for many years because of its inherent 'undruggable...
[期刊论文] 作者:Xiufeng Pang,Mingyao Liu,
来源:黑龙江科技学院学报 年份:2016
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7...
[期刊论文] 作者:Binghe Tan,Mingyao Liu,
来源:中国科学:生命科学英文版 年份:2018
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[期刊论文] 作者:Tianru Jin,Mingyao Liu,
来源:药学学报(英文版) 年份:2020
To the Editor:rnThe coronavirus disease 2019 (COVID-19) pandemic is now spreading over 187 countries or territories, taking away hundreds to thousands of lives...
[会议论文] 作者:Weishi Yu,Dali Li,Mingyao Liu,
来源:2009年亚太地区肿瘤生物学和医学学术会议暨第四届中国中青年肿瘤专家论坛 年份:2009
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LGR4 is a receptor for RANKL that negatively regulates osteoclast differentiation and bone resorptio
[会议论文] 作者:Zhiying Yue,Luo Jian,Mingyao Liu,
来源:上海市细胞生物学学会第9次全体会员代表大会暨第十二届CST细胞生物学青年论坛 年份:2016
Tumor necrosis factor superfamily member 11 (TNFSF11;also known as RANKL) regulates variety of physiological or pathological functions including osteoclast...
[期刊论文] 作者:Xinliang Gao,Wei Liu,Mingyao Liu,,
来源:实用器官移植电子杂志 年份:2017
刘明耀教授是多伦多大学临床医学研究生院院长、外科教授、资深科学家,主要从事肺移植的临床与科研工作。主持科研课题27项,主要参与课题10项,曾荣获伊丽莎白二世女王钻石禧...
[期刊论文] 作者:Shihong Peng,Zhengfang Yi,Mingyao Liu,,
来源:Chinese Journal of Cancer 年份:2017
Prostate cancer(PCa)is the most common male cancer[1,2].PCa initially depends on androgen receptor(AR)signaling for growth and survival.Androgen deprivation the...
[期刊论文] 作者:Xiaohui Zhang,Liren Wang,Mingyao Liu,Dali Li,,
来源:Science China(Life Sciences) 年份:2017
CRISPR/Cas9 is a versatile genome-editing tool which is widely used for modifying the genome of both prokaryotic and eukaryotic organisms for basic research and...
[期刊论文] 作者:Lei JING,Leeann YAO,Michael ZHAO,Li-ping PENG,Mingyao LIU,
来源:中国药理学报(英文版) 年份:2018
Organ transplantation is the most effective therapy for patients with end-stage disease. Preservation solutions and techniques are crucial for donor organ quali...
[期刊论文] 作者:Jing Lv,Jieqiong Wang,Siyu Chang,Mingyao Liu,Xiufeng Pang,
来源:生物化学与生物物理学报(英文版) 年份:2016
...
In vitro and in vivo evaluation of cucurbitacin E on rat hepatic CYP2C11 expression and activity usi
[期刊论文] 作者:Jian Lu,Tonggui Ding,Xuan Qin,Mingyao Liu,Xin Wang,,
来源:Science China(Life Sciences) 年份:2017
This study explored the effects of cucurbitacin E(Cu E), a bioactive compound from Cucurbitaceae, on the metabolism/ pharmacokinetic of tolbutamide, a model CYP...
The preparation of poly(n-butyl actrylate) latexes with high solid, large scale and narrow distribut
[会议论文] 作者:LIU Baijun,ZHANG Mingyao,LIU Shuang,XU Xiaohui,ZHANG Huixuan,
来源:第十四届全国青年材料科学技术研讨会 年份:2013
Seed emulsion polymerization and agglomerating technology are usually used to prepare high solid content latexes with large particle scale.However,it is difficult to obtain narrow distribution and sta...
,Characterization of organic anion transporting polypeptide 1b2 knockout rats generated by CRISPR/Ca
[期刊论文] 作者:Xinrun Ma,Xuyang Shang,Xuan Qin,Jian Lu,Mingyao Liu,Xin Wang,
来源:药学学报(英文版) 年份:2020
Organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1/3) as important uptake transporters play a fundamental role in the transportation of exogenous drugs...
[会议论文] 作者:王哲,Manying Chen,林慧庆,田丰,叶波,Mingyao Liu,
来源:中国医师协会胸外科医师分会2016年会、第七届全国胸外科学术大会暨第二届河南胸外科论坛 年份:2016
...
[会议论文] 作者:Shijie Liu,Yu Qian,Liang Li,Gaigai Wei,Yuting Guan,Dali Li,Mingyao Liu,
来源:第四届细胞结构与功能的信号基础研讨会 年份:2012
Lgr4, one of the newly identified R-Spondinl receptors, potentiates Wnt signaling which is critical for intestinal epithelial homeostasis.However,how Lgr4 f...
Photoelectrochemical regeneration of all vanadium redox species for construction of a solar recharge
[期刊论文] 作者:Shichao Liao,Jingying Shi,Chunmei Ding,Mingyao Liu,Fengqiang Xiong,Nan Wang,Jian Chen,Can Li,
来源:能源化学 年份:2018
Energy storage is pivotal for the continuous utilization of solar energy suffering from the intermittency issue.Herein,we demonstrate a solar rechargeable flow cell (SRFC) based on photoelectrochemical regeneration of vanadium redox species......
[期刊论文] 作者:Fang Lv,Xiaonan Cong,Wenshu Tang,Yiming Han,Yu Tang,Yongrui Liu,Liqiang Su,Mingyao Liu,Mingfei Jin,Zhengfang,
来源:Science China(Life Sciences) 年份:2017
Hemostasis is a major challenge in surgical procedures and traumas. Conventional hemostatic methods have limited efficacy and may cause additional tissue damage...
[会议论文] 作者:Rui Wang,Ping Wang,Yan Wang,Ning Liu,Yunfei Chen,Hui Tang,Su Yu,Kai Zhang,Rong Li,Mingyao Liu,
来源:中国细胞生物学学会全体会员代表大会暨第十二次学术大会 年份:2011
Endothelial cells, which line in the interior surface of all blood vessels, are involved in many aspects of physiological and pathological vascular processes, including angiogenesis, inflammation, and...
Generation of obese rat model by transcription activator-like effector nucleases targeting the lepti
[期刊论文] 作者:Yuting Chen,Wenqing Lu,Na Gao,Yi Long,Yanjiao Shao,Meizhen Liu,Huaqing Chen,Shixin Ye,Xueyun Ma,Mingyao Liu,
来源:Science China(Life Sciences) 年份:2017
The laboratory rat is a valuable mammalian model organism for basic research and drug discovery. Here we demonstrate an efficient methodology by applying transc...
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