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In silico binding mode analysis of andrographolide and its derivatives to mutant and wild-type K-ras
[期刊论文] 作者：Shun Ying QUAH,Pran KishoreDEB,Johnson STANSLAS,,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE To investigate the structural requirements for effective binding of andrographolide(AGP)and its derivatives(SRJ09and SRJ23)to mutant K-ras for inhibit...
[期刊论文] 作者：Johnson STANSLAS,Charng Choon WONG,Hui Chyn WONG,Shun Ying QUAH,Pran Kishore DEB,Sreenivasa Rao SAGINEEDU,
来源：中国药理学与毒理学杂志 年份：2015
We embarked on the discovery of anticancer agents from andrographolide nearly 15 years ago.Thus far,a few lead semisynthetic compounds have been identified,but...
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