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PKPD modeling and simulation and its application in the optimization of therapeutic regimens of anti
[会议论文] 作者：Tianyan Zhou,
来源：第五届定量药理学与新药评价国际会议 年份：2015
Cancer therapy PD of Irreversible Effects: Phase-nonspecific PD of Irreversible Effects: Phase-nonspecific PD of Irreversible Effects: Cell-cycle Specific...
PK/PD modeling and simulation and its application in the optimization of therapeutic regimens of ant
[会议论文] 作者：Tianyan Zhou,
来源：第五届定量药理学与新药评价国际会议 年份：2015
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An integrated PK/PD model to link the frequency of cancer-stem-like cells to tumor volume for suniti
[会议论文] 作者：Siyuan Wang,Xiao Zhu,Tianyan Zhou,Wei Lu,
来源：第五届定量药理学与新药评价国际会议 年份：2015
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Pharmacokinetic-pharmacodynamic modeling of the anti-tumor tumor effect of sunitinib combined with d
[会议论文] 作者：Fangran Hao,Siyuan Wang,Wei Lu,Tianyan Zhou,
来源：第五届定量药理学与新药评价国际会议 年份：2015
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[会议论文] 作者：Yue Qiu,Liang Li,Tianyan Zhou,Wei Lu,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
Background: The aim of this study was to establish a causal disease progression model quantifying the sequential change of biomarkers and their relative values as predictors of different Alzheimers Di...
An integrated PK/PD model to link the frequency of cancer-stem-like cells to tumor volume for suniti
[会议论文] 作者：Siyuan Wang,Xiao Zhu,Tianyan Zhou,Wei Lu,
来源：第五届定量药理学与新药评价国际会议 年份：2015
Background: Breast cancer is one of the leading causes of mortality among women worldwide.As a potent multi-targeted receptor tyrosine kinase inhibitor, sunitinib has shown promising results in clinic...
Pharmacokinetic-pharmacodynamic modeling of the anti-tumor tumor effect of sunitinib combined with d
[会议论文] 作者：Fangran Hao,Siyuan Wang,Wei Lu,Tianyan Zhou,
来源：第五届定量药理学与新药评价国际会议 年份：2015
Background: Lung cancer is the most lethal form of cancer in the world.Sunitinib is a promising multi-targeted receptor tyrosine kinase (RTK) inhibitor with activity against vascular endothelial growt...
Mechanism-Based Pharmacokinetic-Pharmacodynamic-Disease Progression Model for Perindopril in Spontan
[会议论文] 作者：Xuan Zhou,Dewei Shang,Jian Li,Liang Li,Tianyan Zhou,Wei Lu,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
The aim of the present study was to development a pharmacokinetic/pharmacodynamic (PK/PD) model for the characterization ofperindopril effect in spontaneously hypertensive rats (SHRs) while taking int...
Application of Model-Based Methods to Characterize Exenatide-Loaded Double-Walled Microspheres: In V
[会议论文] 作者：Xingang Li,Liang Li,Xipei Wang,Yupeng Ren,Tianyan Zhou,Wei Lu,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
Exenatide (glucagon-like-peptide-1 analogue) was authorized for marketing in the European Union in November 2006 and was approved by FDA in April 2005.To improve compliance, exenatide double-walled mi...
[会议论文] 作者：QiongWu,Hanqing Li,Xiaoliang Cheng,Xipei Wang,Liang Li,Tianyan Zhou,Wei Lu,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium 年份：2013
...
[会议论文] 作者：QiongWu,Hanqing Li,Xiaoliang Cheng,Xipei Wang,Liang Li,Tianyan Zhou,Wei Lu,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
Aim:Erlotinib is used to treat non-small-cell lung cancer (NSCLC), which targets epidermal growth factor receptor (EGFR) tyrosine kinase.The aim of this study was to investigate the relationship betwe...
Preclinical Pharmacokinetic/Pharmacodynamic Models to Predict Schedule-Dependent Interaction Between
[会议论文] 作者：Mengyao Li,Hanqing Li,Xiaoliang Cheng,Xipei Wang,Liang Li,Tianyan Zhou,Wei Lu,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
Purpose:To investigate the pharmacological effects of differenterlotinib (ER) and gemcitabine (GM) combination schedules byin vitro and in vivo experiments and PK/PD models in non-smallcell lung cance...
Population Pharmacokinetics-pharmacodynamics modeling of risperidone and its active metabolite in Ch
[会议论文] 作者：Shuangmin Ji,Dewei Shang,Anning Li,Liang Li,Tianyan Zhou,Chuanyue Wang,Wei Lu,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
Background: Risperidone, an anatypical antipsychotic agent, characterized as an antagonist of dopaminergic and serotonergic receptors, is now widely used in the treatment of patients with positive sym...
[会议论文] 作者：Xipei Wang,Dewei Shang,Yuguan Wen,Liang Li,Tianyan Zhou,Xiyong Yu,Wei Lu,Chuanyue Wang,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
Background: The aim of this study was to characterize the time course of the Positive and Negative Syndrome Scale (PANSS) scores of clozapine in Chinese sch...
Predictability of reported population pharmacokinetic models of vancomycin in Chinese adult patients
[会议论文] 作者：Chenhui Deng,Wei Lu,Taotao Liu,Kehua Wu,Siyuan Wang,Liang Li,Hua Lu,TianYan Zhou,Daohai Cheng,Xiaobin,
来源：第四届定量药理学与新药评价国际会议·2013(The 4th International Symposium in Qu 年份：2013
Objective: There are numerous studies on population pharmacokinetics of vancomycin in adult patients.However, there is no such research for Chinese adult pa...
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