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[会议论文] 作者：Toshihiko Hayashi,Toshio Nishiyama,Yasukazu Nakayama,
来源：International Conference of Traditional Chinese Medicine Pha 年份：2012
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Effect of saikosaponin b1 on collagen production by dermal fibroblasts in dermal tissue model and in
[会议论文] 作者：Toshihiko HAYASHI,Toshio NISHIYAMA,Yasukazu NAKAYAMA,
来源：第二届世界天然药物和传统药物药理学学术会议 年份：2012
AIM Human dermal fibroblasts in a dermal tissue model show reduced proliferation or cell-matrix contact inhibition (CMI), distinct from cell-cell contact inhibition (CCI) at confluent.Epidermal growth...
,Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cell
[期刊论文] 作者：Nan ZHENG,Lu LIU,Wei-wei LIU,Fei LI,Toshihiko HAYASHI,Shin-ichi TASHIRO,Satoshi ONODERA,
来源：中国药理学报（英文版） 年份：2017
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,Activation of p53 contributes to pseudolaric acid B-induced senescence in human lung cancer cells i
[期刊论文] 作者：Guo-dong YAO,Jing YANG,Qiang LI,Ye ZHANG,Min QI,Si-miao FAN,Toshihiko HAYASHI,
来源：中国药理学报（英文版） 年份：2016
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Brain dysfunction induced by amyloid β25-35 combined with excessive exercise in rats is protected by
[会议论文] 作者：Di Lei,Xiaoyu Song,Biao Zhou,Pingping Zhang,Mingyu Xia,Toshihiko Hayashi,Takashi Ikejima,
来源：2015全国老年痴呆与认知障碍相关疾病学术大会 年份：2015
Alzheimers disease (AD), a neurodegenerative disease,is seriously threatening the health of the elderly.In recent years,exercise is accepted as a kind of physical fitness.It is reported that moderate...
[会议论文] 作者：Biao Zhou,Xiaoyu Song,Pingping Zhang,Di Lei,Mingyu Xia,Toshihiko Hayashi,Takashi Ikejima,
来源：2015全国老年痴呆与认知障碍相关疾病学术大会 年份：2015
This study aimed to investigate whether silibinin could improve the learning and memory, and antioxidant abilities of Alzheimers diseases (AD) rats.The 60 rats were randomly divided into six groups: n...
[会议论文] 作者：Xiaoyu Song,Biao Zhou,Pingping Zhang,Di Lei,Guodong Yao,Mingyu Xia,Toshihiko Hayashi,Takashi Ikejima,
来源：2015全国老年痴呆与认知障碍相关疾病学术大会 年份：2015
In this study we examined the effects of silibinin, a flavonoid derived from the herb milk thistle, on impaired learning and memory of the rat model with brain inflammation induced by lipopolysacchari...
[期刊论文] 作者：Guo-dong YAO,Jing YANG,Xiu-xiu LI,Xiao-yu SONG,Toshihiko HAYASHI,Shin-ichi TASHIRO,Satoshi ONODERA,Shao-jiang,
来源：中国药理学报（英文版） 年份：2017
Pseudolaric acid B (PAB),a diterpene acid isolated from the root bark of Pseudolarix kaempferi Gordon,exerts anti-tumor effects in several cancer cell lines.Our...
[会议论文] 作者：Xiaoyu Song,Qifeng Shi,Pingping Zhang,Di Lei,Biao Zhou,Guodong Yao,Mingyu Xia,Toshihiko Hayashi,Takashi,
来源：2015全国老年痴呆与认知障碍相关疾病学术大会 年份：2015
Objective: Silibinin, a major bioactive flavanone derived from the herb milk thistle, has potent anti-inflammatory and antioxidant activities.The damages caused by exhaustive exercise have been concen...
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