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Evaluation of human monoclonal antibody toxicity,toxicokinetics and immunogenicity in cynomolgus mon
[期刊论文] 作者：YU Hong,Patricia RYAN,LIANG Mei-na,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,QIAO Jun-wen,REN Jin,,
来源：中国药理学与毒理学杂志 年份：2013
OBJECTIVE The aim of this study was to characterize the toxicity of the antibody and in particular,the exposure-response relationship of the immune-mediated tox...
Concurrent CD44s and STAT3 expression in human clear cell renal cellular carcinoma and its impact on
[会议论文] 作者：Jun Qin,Bo Yang,Wei-Jun Qin,Guo-Jun Wu,Chen Shao,Bao-Qin Xu,Jian-Lin Yuan,Ling Li,
来源：GTAUF2014 & APSMHA2014第六届长城泌尿男科转化医学论坛暨第七届亚太男性健康与抗衰老研究学会年会 年份：2014
Although CD44 was overexpressed and considered as a useful prognostic marker in renal cell carcinoma, the prognostic role of CD44s in clear cell renal cell carcinoma (ccRCC) remains controversial.More...
Evaluation of human monoclonal antibody toxicity, toxicokinetics and immunogenicity in cynomolgus mo
[会议论文] 作者：YU Hong,Patricia RYAN,LIANG Mei-na,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,QIAO Jun-wen,REN Jin,
来源：2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份：2013
OBJECTIVE The aim of this study was to characterize the toxicity of the antibody and in particular, the exposure-response relationship of the immune-mediated toxicity between these two dose regimens.M...
Evaluation of cisplatin-induced toxicity in cynomolgus macaques including assessment of potential bi
[期刊论文] 作者：YU Hong,Sonya GALES,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,QIAO Jun-wen,REN Jin,CHEN Ya-fei,Russell,
来源：中国药理学与毒理学杂志 年份：2013
OBJECTIVE Cisplatin-induced nephrotoxicity has been characterized previously in animals and humans.Two studies were conducted in cynomolgus macaques to assess t...
Evaluation of cisplatin-induced toxicity in cynomolgus macaques including assessment of potential bi
[会议论文] 作者：YU Hong,Lew KINTER,Nigel BARRASS,Sonya GALES,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,QIAO Jun-wen,REN,
来源：2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份：2013
OBJECTIVE Cisplatin-induced nephrotoxicity has been characterized previously in animals and humans.Two studies were conducted in cynomolgus macaques to assess the nephrotoxicity of cisplatin and to co...
Evaluation of imipenem toxicity in cynomolgus macaques including assessment of biomarkers of renal d
[期刊论文] 作者：YU Hong,Sonya GALES,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,HU Li-ping,QIAO Jun-wen,REN Jin,CHEN Ya-fei,
来源：中国药理学与毒理学杂志 年份：2013
OBJECTIVE To assess the nephrotoxicity of imipenem and to correlate the pathogenesis of lesions in the kidney with changes in urinary biomarkers of kidney toxic...
Evaluation of imipenem toxicity in cynomolgus macaques including assessment of biomarkers of renal d
[会议论文] 作者：YU Hong,Russell BIALECKI,Lew KINTER,Nigel BARRASS,Sonya GALES,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,
来源：2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份：2013
OBJECTIVE To assess the nephrotoxicity of imipenem and to correlate the pathogenesis of lesions in the kidney with changes in urinary biomarkers of kidney toxicity.METHODS Study #1, 11 monkeys (2-3/se...
Change of the cell cycle after flutamide treatment in prostate cancer cells and its molecular mechan
[期刊论文] 作者：Wang,Chen Shao,Chang-Hong Shi,Lei Zhang,Hong-Hong Yue,Peng-Fei Wang,Bo Yang,Yun-Tao Zhang,Fan Liu,Wei-Jun Qin,
来源：亚洲男性学杂志(英文版) 年份：2005
Aim: To explore the effect of androgen receptor (AR) on the expression of the cell cycle-related genes, such as CDKN1A and BTG1, in prostate cancer cell line LNCaP. Methods: After AR antagonist flutamide treatment and confirmation of its ef......
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