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[期刊论文] 作者：Ai-Ming Yu,Xiao-bo Zhong,,
来源：Acta Pharmaceutica Sinica B 年份：2016
Drug metabolism and transport in human organs,such as in the liver,intestine,and kidney,control the concentrations of a drug and its metabolites in the circulat...
Regulation of basal and induced expression of P450s in liver cells by a transcription factor network
[会议论文] 作者：Liming Chen,Yifan Bao,Xiao-bo Zhong,
来源：2017年第三届岭南国际DMPK论坛 年份：2017
Cytochrome P450 (P450) enzymes play a critical role in metabolism of xenobiotics, including drugs and toxicants. Control of P450 expression can directly influen...
Regulation of basal and induced expression of P450s in liver cells by a transcription factor network
[会议论文] 作者：Liming Chen,Yifan Bao,Xiao-bo Zhong,
来源：2017年第三届岭南国际DMPK论坛 年份：2017
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,Role of farnesoid X receptor in establishment of ontogeny of phase-Ⅰ drug metabolizing enzyme genes
[期刊论文] 作者：Lai Peng,Stephanie Piekos,Grace L.Guo,Xiao-bo Zhong,
来源：药学学报（英文版） 年份：2016
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[期刊论文] 作者：Pengcheng Wang,Komal Pradhan,Xiao-bo Zhong,Xiaochao Ma,,
来源：Acta Pharmaceutica Sinica B 年份：2016
Isoniazid(INH) is highly effective for the management of tuberculosis.However,it can cause liver injury and even liver failure.INH metabolism has been thought t...
[期刊论文] 作者：Lai Peng,Stephanie Piekos,Grace L.Guo,Xiao-bo Zhong,,
来源：Acta Pharmaceutica Sinica B 年份：2016
The expression of phase-I drug metabolizing enzymes in liver changes dramatically during postnatal liver maturation.Farnesoid X receptor(FXR) is critical for bi...
,Impact of obese levels on the hepatic expression of nuclear receptors and drug-metabolizing enzymes
[期刊论文] 作者：Pei Wang,Xueyan Shao,Yifan Bao,Junjie Zhu,Liming Chen,Lirong Zhang,Xiaochao Ma,Xiao-bo Zhong,
来源：药学学报（英文版） 年份：2020
The prevalence of obesity-associated conditions raises new challenges in clinical medication.Although altered expression of drug-metabolizing enzymes (DMEs) has...
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