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Design,synthesis and biological evaluation of novel sorafenib analogs bearing a 4-(2-(dimethylamino)
[会议论文] 作者：Mingze Qin,Lei Chen,Xin Zhai,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
Multikinase inhibitors have emerged as new approaches for cancer therapy in recent years,notonly for their outstanding antitumor activities,but also for the...
Design,synthesis and biological evaluation of novel sorafenib analogs bearing a 4-(2-(dimethylamino)
[会议论文] 作者：Mingze Qin,Lei Chen,Xin Zhai,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
Multikinase inhibitors have emerged as new approaches for cancer therapy in recent years,notonly for their outstanding antitumor activities,but also for their diverse mechanisms of action exertedin di...
[期刊论文] 作者：Rong Dong Li,Xin Zhai,Yan Fang,
来源：中国化学快报：英文版 年份：2007
5H-pyridazino 的一个新奇系列[4,5-b ] 吲哚被设计并且综合了以便发现新奇有势力反癌症混合物。结构被 1H NMR 和 MS 证实。他们对二根癌症房间线的 antiproliferative 活动...
[期刊论文] 作者：Dong Chen Xin Zhai Qiu Hui Yua,
来源：中国化学快报：英文版 年份：2010
A series of 1H-benzimidazol-5-ol derivatives were synthesized and evaluated for their anti-hepatitis B virus(HBV) activity and cytotoxicity in HepG2.2.15 ce...
[期刊论文] 作者：Shu Lan Zhang Xin Zhai Shi Jia,
来源：中国化学快报：英文版 年份：2010
一系列 quinoline-3-carbonitrile 衍生物被设计并且综合。他们在对四根癌症房间线(A549， HT-29， MDA-MB-231 和 SMMC-7721 ) 的 vitro 的 cytotoxicity 被标准 MTT 试金评估。...
[期刊论文] 作者：Xin Zhai,Nan Jiang,Ke Liang Zh,
来源：中国化学快报：英文版 年份：2009
在我们识别新奇有势力反癌症代理人的努力，我们综合了一系列 2,7-disubstituted triazolo [1,5-a ] 嘧啶(6 –； 16 ) 。他们对 Bel-7402， HT-1080 和 WI-38 房间线的 antip...
[期刊论文] 作者：Fan Zhang,Xin Zhai,Li Juan Che,
来源：中国化学快报（英文版） 年份：2004
A series of 2,5-disubstituted pyrimido[5,4-c]quinoline derivatives were synthesized and their cytotoxic activity against H460, HT-29 and MDA-MB-231 cell lines w...
Design, synthesis and biological evaluation of new rhodacyanine analogues as potential antitumor age
[期刊论文] 作者：Yang Xiong Li,Xin Zhai,Wei Ke,
来源：中国化学快报（英文版） 年份：2004
In an attempt to develop potent antitumor agents,new rhodacyanine analogues containing the pyridinium ring (5a-5h),the isoquinolinium ring (6a-6c) and the quino...
[期刊论文] 作者：Rong Dong Li,Xin Zhai,Yan Fang,
来源：中国化学快报（英文版） 年份：2004
A novel series of 5H-pyridazino[4,5-b]indoles were designed and synthesized in order to find novel potent anticancer compounds. The structures were confirmed by...
Design, synthesis and antiproliferative activity of novel 2,7-disubstituted triazolo[1,5-a]pyrimidin
[期刊论文] 作者：Xin Zhai,Nan Jiang,Ke Liang Zh,
来源：中国化学快报（英文版） 年份：2004
In our efforts to identify novel potent anticancer agents, we synthesized a series of 2,7-disubstituted triazolo[1,5-a]pyrimidines (6-16). Their antiproliferati...
[期刊论文] 作者：Dong Chen,Xin Zhai,Qiu Hui Yua,
来源：中国化学快报（英文版） 年份：2004
A series of IH-benzimidazol-5-ol derivatives were synthesized and evaluated for their anti-hepatitis B virus(HBV)activity and eytotoxicity in HepG2.2.15 cells.H...
[期刊论文] 作者：Shu Lan Zhang,Xin Zhai,Shi Jia,
来源：中国化学快报（英文版） 年份：2004
A series of quinoline-3-carbonitrile derivatives were designed and synthesized.Their cytotoxicity in vitro against four cancer cell lines (A549,HT-29,MDA-MB-231...
Design, synthesis and antiproliferative activity of novel 2,7-disubstituted triazolo[1,5-a]pyrimidin
[期刊论文] 作者：Xin Zhai,Nan Jiang,Ke Liang Zh,
来源：黑龙江科技学院学报 年份：2009
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7...
Design, synthesis and biological evaluation of new rhodacyanine analogues as potential antitumor age
[期刊论文] 作者：Yang Xiong Li,Xin Zhai,Wei Ke,
来源：黑龙江科技学院学报 年份：2012
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7...
[期刊论文] 作者：Xin Zhai,Juan Li,Lei He,Su Zhe,
来源：中国化学快报：英文版 年份：2008
八新奇 1,4-disubstituted phthalazines (7 14 ) 被设计并且综合。所有综合混合物的结构被红外， 1H NMR， 13C NMR， MS 和元素的分析证实。他们的在里面对癌症房间线(Bel-7402...
[期刊论文] 作者：Xin Zhai,Juan Li,Lei He,Su Zhe,
来源：中国化学快报（英文版） 年份：2004
Eight novel 1,4-disubstituted phthalazines (7-14) were designed and synthesized. The structures of all the synthesizedcompounds were confirmed by IR, 1H NMR,13C...
Synthesis and cytotoxic activity of novel 2,6-disubstituted-4-morpholinothieno[3,2-d]pydmidines as p
[期刊论文] 作者：Wu Fu Zhu,Xin Zhai,Sai Li,Yun,
来源：中国化学快报（英文版） 年份：2004
A series of 2,6-disubstituted-4-morpholinothieno[3,2-d]pyrimidine derivatives were synthesized and their cytotoxic activity against H460,HT-29,MDA-MB-231,U87MG...
Synthesis and cytotoxic activity of novel 2,6-disubstituted-4-morpholinothieno[3,2-d]pydmidines as p
[期刊论文] 作者：Wu Fu Zhu,Xin Zhai,Sai Li,Yun,
来源：黑龙江科技学院学报 年份：2012
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7...
Design,Synthesis and Antitumor Activities of Novel Tricydic 1-Anilino-5H-Pyridazino[4,5-b] Indole An
[会议论文] 作者：Xin ZHAI,Peng YAO,Wei JIA,Ping GONG,
来源：2007年全国药物化学学术研讨会 年份：2007
...
Design,Synthesis and Antitumor Activities of Novel Tricydic 1-Anilino-5H-Pyridazino[4,5-b] Indole An
[会议论文] 作者：Xin ZHAI,Peng YAO,Wei JIA,Ping GONG,
来源：2007年全国药物化学学术研讨会 年份：2007
...
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