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[期刊论文] 作者:Yan CAI,Li-kun GONG,Xin-ming QI,Xiang-hong LI,Jin REN,
来源:中国药理学报(英文版) 年份:2005
Aim: To investigate the mitochondria-initiated apoptosis pathway involved in Carbon tetrachloride (CCl4) hepatotoxicity in vitro. Methods: Several cytotoxicity...
,ROS generated by CYP450, especially CYP2E1,mediate mitochondrial dysfunction induced by tetrandrine
[期刊论文] 作者:Xin-ming QI,Ling-ling MIAO,Yan CAI,Li-kun GONG,Jin REN,
来源:中国药理学报(英文版) 年份:2013
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,Timosaponin A3 induces hepatotoxicity in rats through inducing oxidative stress and down-regulating
[期刊论文] 作者:Zhi-tao WU,Xin-ming QI,Jing-jing SHENG,Lei-lei MA,Xuan NI,Jin REN,Cheng-gang HUANG,
来源:中国药理学报(英文版) 年份:2014
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[期刊论文] 作者:Lin-lin LIU,Li-kun GONG,Xin-ming QI,Yan CAI,Hui WANG,Xiong-fei WU,Ying XIAO,Jin REN,
来源:中国药理学报(英文版) 年份:2005
Aim: Correlation of cytochrome P450 (CYPs) with preneoplastic changes in the early stage of hepatocarcinogenesis is still unclear. To detect the expression of c...
[期刊论文] 作者:Fang-ping CHEN,Li-kun GONG,Ling ZHANG,Hui WANG,Xin-ming QI,Xiong-fei WU,Ying XIAO,Yan CAI,Lin-lin LIU,
来源:中国药理学报(英文版) 年份:2007
Aim: Angiotensin Ⅱ is believed to play an important role in tissue repair and remodeling in lungs by the angiotensin type Ⅰ (ATI) receptor via a number of pot...
Aristolochic acid I promoted clonal expansion but did not induce hepatocellular carcinoma in adult r
[期刊论文] 作者:Yong-zhen Liu,Heng-lei Lu,Xin-ming Qi,Guo-zhen Xing,Xin Wang,Pan Yu,Lu Liu,Fang-fang Yang,Xiao-lan Ding,
来源:中国药理学报(英文版) 年份:2021
Aristolochic acid I (AAI) is a well-known nephrotoxic carcinogen,which is currently reported to be also associated with hepatocellular carcinoma (HCC).Whether AAI is a direct hepatocarcinogen remains controversial.In this study we investiga......
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