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Furmonertinib(Alflutinib,AST2818)is a potential positive control drug comparable to rifampin for eva
[期刊论文] 作者:Ya-li Wu,Ya-ru Xue,Zi-tao Guo,Zhen-dong Chen,Xin-yu Ge,Da-fang Zhong,Xing-xing Diao,
来源:中国药理学报(英文版) 年份:2022
Furmonertinib(Alflutinib,AST2818),as a third-generation epidermal growth factor receptor inhibitor with an advanced efficacy and a relatively wide safety window,has been commercially launched in China recently.However,previous clinical stud......
,Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments
[期刊论文] 作者:Yang Xie,Xu Zhou,Hu Pei,Ming-cang Chen,Zhao-lin Sun,Ya-ru Xue,Xiao-ting Tian,Cheng-gang Huang,
来源:中国药理学报(英文版) 年份:2018
Timosaponin A3,a saponin in Zhimu,elicited hepatotoxicity via oxidative stress.However,the clinical medication of Zhimu has been historically regarded as safe,p...
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice vi
[期刊论文] 作者:Ya-ru Xue,Sheng Yao,Qian Liu,Zhao-liang Peng,Qiang-qiang Deng,Bo Liu,Zheng-hua Ma,Le Wang,Hu Zhou,Yang,
来源:中国药理学报(英文版) 年份:2020
In general,anti-inflammatory treatment is considered for multiple liver diseases despite the etiology.But current drugs for alleviating liver inflammation have...
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