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[期刊论文] 作者:LIAO Sha,ZHANG Zhen-qing, 来源:2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份:2013
OBJECTIVE To study toxicokinetics of A-1 at the three doses adopted in toxicology research, and explore the relationship between exposure level and toxicity in order to provide information to safety e...
[期刊论文] 作者:LIAO Sha,ZHANG Zhen-qing,, 来源:中国药理学与毒理学杂志 年份:2013
OBJECTIVE To introduce a novel surrogate analyte approach for definitive quantitation of endogenous drugs using LC-MS-based technology in biological samples.MET...
[会议论文] 作者:LIAO Sha,ZHANG Zhen-qing, 来源:2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份:2013
OBJECTIVE To introduce a novel surrogate analyte approach for definitive quantitation of endogenous drugs using LC-MS-based technology in biological samples.METHODS We searched PubMed for articles pub...
[期刊论文] 作者:Zhang Zhen-Qing,Liu Zheng-Dong,Zhao Shun-Cai,Zheng Jun,Ji Yan-Fang,Liu Nian, 来源:中国物理B(英文版) 年份:2011
[期刊论文] 作者:Zhan-le ZHENG,Xian YU,Guo-qiang XU,Wei CHEN,Ying-ze ZHANG,Zhen-qing JIAO, 来源:华中科技大学学报(医学英德文版) 年份:2014
[会议论文] 作者:ZHUANG Xiao-Mei,XIAO Wei-Bin,ZHONG Yu-Huan,LU Fei,LU Chuang,ZHANG Zhen-qing,LI Hua, 来源:2015年第一届药代动力学朝阳论坛 年份:2015
Accurate prediction of human pharmacokinetics from preclinical in vivo and in vitro data remains a critical goal in the drug discovery and development process to minimize risk during first-in-human st...
[期刊论文] 作者:MENG Yao,YI Lin,CHEN Lei,HAO Jie,LI Du-Xin,XUE Jie,XU Nai-Yu,ZHANG Zhen-Qing, 来源:中国天然药物 年份:2019
Polysaccharide from traditional Chinese herb,Saposhnikovia divaricata (Turcz.) Schischk.(SD) was extracted,fractionated and characterized in this work.Four fractions were prepared.Their molecular weight,monosaccharide compositions,linkage m......
[会议论文] 作者:LIAO Sha,ZHANG Wen-peng,LI Jin,ZHANG Tian-hong,ZHANG Zhen-qing,ZHANG Xiu-juan,WANG Xiao-ying,LUO Huan, 来源:2015第11届全国药物和化学异物代谢学术会议 年份:2015
  A simple and sensitive liquid chromatography-tandem mass spectrometric (LC-MS/MS) method based on surrogate analyte stategy was developed for the measuremen...
[会议论文] 作者:SONG Xin-yi,LUO Huan,LI Jing-lai,ZHANG Tian-hong,ZHANG Wen-peng,WANG Xiao-ying,WANG Juan,WU Ning,ZHANG Zhen-qing, 来源:2015第11届全国药物和化学异物代谢学术会议 年份:2015
A simple and sensitive liquid chromatography-tandem mass spectrometric (LC-MS/MS) method based on surrogate analyte stategy was developed for the measurement of endogenous agmatine in rat tissues....
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