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[期刊论文] 作者:LIAO Sha,ZHANG Zhen-qing,
来源:2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份:2013
OBJECTIVE To study toxicokinetics of A-1 at the three doses adopted in toxicology research, and explore the relationship between exposure level and toxicity in order to provide information to safety e...
Surrogate analyte approach:a novel strategy for definitive quantitation of endogenous biomolecules b
[期刊论文] 作者:LIAO Sha,ZHANG Zhen-qing,,
来源:中国药理学与毒理学杂志 年份:2013
OBJECTIVE To introduce a novel surrogate analyte approach for definitive quantitation of endogenous drugs using LC-MS-based technology in biological samples.MET...
[会议论文] 作者:LIAO Sha,ZHANG Zhen-qing,
来源:2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份:2013
OBJECTIVE To introduce a novel surrogate analyte approach for definitive quantitation of endogenous drugs using LC-MS-based technology in biological samples.METHODS We searched PubMed for articles pub...
[期刊论文] 作者:Zhang Zhen-Qing,Liu Zheng-Dong,Zhao Shun-Cai,Zheng Jun,Ji Yan-Fang,Liu Nian,
来源:中国物理B(英文版) 年份:2011
...
Four Pins Assisted Reduction of Complex Segmental Femoral Fractures: a Technique for Closed Reductio
[期刊论文] 作者:Zhan-le ZHENG,Xian YU,Guo-qiang XU,Wei CHEN,Ying-ze ZHANG,Zhen-qing JIAO,
来源:华中科技大学学报(医学英德文版) 年份:2014
...
Application of physiologically based pharmacokinetic model to assess xenobiotic disposition in human
[会议论文] 作者:ZHUANG Xiao-Mei,XIAO Wei-Bin,ZHONG Yu-Huan,LU Fei,LU Chuang,ZHANG Zhen-qing,LI Hua,
来源:2015年第一届药代动力学朝阳论坛 年份:2015
Accurate prediction of human pharmacokinetics from preclinical in vivo and in vitro data remains a critical goal in the drug discovery and development process to minimize risk during first-in-human st...
Purification, structure characterization and antioxidant activity of polysaccharides from Saposhniko
[期刊论文] 作者:MENG Yao,YI Lin,CHEN Lei,HAO Jie,LI Du-Xin,XUE Jie,XU Nai-Yu,ZHANG Zhen-Qing,
来源:中国天然药物 年份:2019
Polysaccharide from traditional Chinese herb,Saposhnikovia divaricata (Turcz.) Schischk.(SD) was extracted,fractionated and characterized in this work.Four fractions were prepared.Their molecular weight,monosaccharide compositions,linkage m......
Accurate Quantification of endogenous agmatine in rat tissues by LC-MS/MS based on surrogate analyte
[会议论文] 作者:LIAO Sha,ZHANG Wen-peng,LI Jin,ZHANG Tian-hong,ZHANG Zhen-qing,ZHANG Xiu-juan,WANG Xiao-ying,LUO Huan,
来源:2015第11届全国药物和化学异物代谢学术会议 年份:2015
A simple and sensitive liquid chromatography-tandem mass spectrometric (LC-MS/MS) method based on surrogate analyte stategy was developed for the measuremen...
Accurate Quantification of endogenous agmatine in rat tissues by LC-MS/MS based on surrogate analyte
[会议论文] 作者:SONG Xin-yi,LUO Huan,LI Jing-lai,ZHANG Tian-hong,ZHANG Wen-peng,WANG Xiao-ying,WANG Juan,WU Ning,ZHANG Zhen-qing,
来源:2015第11届全国药物和化学异物代谢学术会议 年份:2015
A simple and sensitive liquid chromatography-tandem mass spectrometric (LC-MS/MS) method based on surrogate analyte stategy was developed for the measurement of endogenous agmatine in rat tissues....
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