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[期刊论文] 作者：Jun-Chao WU,Zhong-Qin LIANG,Zheng-Hong QIN,
来源：生物化学与生物物理学报（英文版） 年份：2006
The quality control (QC) system of the endoplasmic reticulum (ER) is an important monitoring mechanism in the protein maturation process, which ensures export o...
[期刊论文] 作者：Ya-ping YANG,Zhong-qin LIANG,Zhen-lun GU,Zheng-hong QIN,
来源：中国药理学报(英文版) 年份：2005
Autophagy is a major cellular pathway for the degradation of long-lived proteins and cytoplasmic organelles in eukaryotic cells. A large number of intracellular...
[期刊论文] 作者：Li ZHANG,Zhen-lun GU,Zheng-hong QIN,Zhong-qin LIANG,
来源：中国药理学报(英文版) 年份：2008
Aim: To determine whether curcumin prevents the adhesion of platelets to brain microvascular endothelial cells (BMECs) cultured in vitro. Methods: [3H]Ad-chine-...
[期刊论文] 作者：Wei-Yan ZHANG,Zhen-Lun GU,Zhong-Qin LIANG,Zheng-Hong QIN,
来源：神经科学通报（英文版） 年份：2006
Huntington disease (HD) is a chronic autosomal-dominant neurodegenerative disease. The gene coding Huntingtin has been identified, but the pathogenic mechanisms...
,Prostaglandin A1 inhibits increases in intracellular calcium concentration, TXA2 production and pla
[期刊论文] 作者：Yi ZHU,Zhen-lun GU,Zhong-qin LIANG,Hui-lin ZHANG,Zheng-hong QIN,
来源：中国药理学报（英文版） 年份：2006
Aim: In our previous studies we found that cyclopentenane prostaglandin A1 (PGA1) had neuroprotective effects in a rodent ischemic model. In the present study w...
,Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cel
[期刊论文] 作者：Ya-ping YANG,Zhong-qin LIANG,Bo GAO,Yan-li JIA,Zheng-hong QIN,
来源：中国药理学报（英文版） 年份：2008
Aim: To evaluate the contribution of an autophagic mechanism to the As2O3-induced death of human acute myeloid leukaemia cell line HL60 cells. Methods: The grow...
,Inhibition of cathepsin L sensitizes human glioma cells to ionizing radiation in vitro through NF-k
[期刊论文] 作者：Neng YANG,Pan WANG,Wen-juan WANG,Yun-zhen SONG,Zhong-qin LIANG,
来源：中国药理学报（英文版） 年份：2015
...
,Autophagy is involved in cytotoxic effects of crotoxin in human breast cancer cell line MCF-7 cells
[期刊论文] 作者：Ci-hui YAN,Ya-ping YANG,Zheng-hong QIN,Zhen-lun GU,Paul REID,Zhong-qin LIANG,
来源：中国药理学报（英文版） 年份：2007
Aim: To investigate the role of crotoxin (CrTX)-induced autophagy in the death of MCF-7 cells, a caspase-3-deficient, human breast cancer cell line. Methods: Cu...
Bilobalide inhibits 6-OHDA-induced activation of NF-κB and loss of dopaminergic neurons in rat subst
[期刊论文] 作者：Ling-yun LI,Xi-lin ZHAO,Xi-feng FEI,Zhen-lun GU,Zheng-hong QIN,Zhong-qin LIANG,
来源：中国药理学报（英文版） 年份：2008
Aim: To investigate the offect of bilobalide on the activation of NF-κB, and apoptasis of dopaminergic neurons induced by 6-hydroxydopamine (6-OHDA). Methods:...
[期刊论文] 作者：Chun-gen XING,Bao-song ZHU,Hui-hui LIU,Fang LIN,Hui-hua YAO,Zhong-qin LIANG,Zheng-hong QIN,
来源：中国药理学报（英文版） 年份：2008
Aim:To study the effects of LY294002, an inhibitor of class Ⅰ phosphatidylinositol 3-kinase (PI3K), on proliferation and apoptosis of SGC7901 gastric cancer ce...
,Cathepsin L suppression increases the radiosensitivity of human glioma U251 cells via G2/M cell cyc
[期刊论文] 作者：Qing-qing ZHANG,Wen-juan WANG,Jun LI,Neng YANG,Gang CHEN,Zhong WANG,Zhong-qin LIANG,
来源：中国药理学报（英文版） 年份：2015
...
,A miRNA-200c/cathepsin L feedback loop determines paclitaxel resistance in human lung cancer A549 c
[期刊论文] 作者：Yi-fan ZHAO,Mei-ling HAN,Ya-jie XIONG,Long WANG,Yao FEI,Xiao SHEN,Ying ZHU,Zhong-qin LIANG,
来源：中国药理学报（英文版） 年份：2018
Cathepsin L (CTSL), a cysteine protease, is closely related to tumor occurrence, development, and metastasis, and possibly regulates cancer cell resistance to c...
p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autoph
[会议论文] 作者：Yan Wang,Xiao-Xia Dong,Yi Cao,Zhong-Qin Liang,Rong Han,Jun-Chao Wu,Zhen-Lun Gu,Zheng-Hong Qin,
来源：江苏省药理学会第六届学术研讨会 年份：2012
The present study sought to investigate mechanisms by which p53 induction contributes to excitotoxic neuronal injury.Rats were intrastriatally administered the N-methyl-d-aspartate (NMDA) receptor ago...
,Cathepsin L induced PC-12 cell apoptosis via activation of B-Myb and regulation of cell cycle prote
[期刊论文] 作者：Xiao Shen,Yi-fan Zhao,Shu-qing Xu,Long Wang,Hui-min Cao,Ying Cao,Ying Zhu,Yan Wang,Zhong-qin Liang,
来源：中国药理学报（英文版） 年份：2019
Cathepsin L (CTSL),a cysteine protease,is responsible for the degradation of a variety of proteins.It is known to participate in neuronal apoptosis associated w...
[期刊论文] 作者：Yun-zhen Song,Ying Zhu,Wen-qing Zuo,Yi-fan Zhao,Xiao Shen,Wen-juan Wang,Ya-li Liu,Jun-chao Wu,Zhong-qin Liang,
来源：中国药理学报（英文版） 年份：2020
Olanzapine is an antipsychotic drug used to treat patients with schizophrenia due to its lower incidence of extrapyramidal symptoms.Previous studies have shown...
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