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Discovery of [1,2,3]triazolo[4,5-d]pyrimidine derivatives as highly potent, selective, and cellularl
Ubiquitin specific peptidase 28 (USP28) is closely associated to the occurrence and development of various malignancies,......
以卤代烃、邻甲基苯胺、氰基乙酸和乙酰氯为原料,经取代、成环、偶联和关环4步反应,用微波法合成了9个[1,2,3]三唑-[4,5-d]嘧啶酮......