Lupusnephritis相关论文
目的:1.探究S1P及其受体在狼疮肾炎中的表达情况2.探究S1P/S1PR1信号通路在狼疮肾炎中发挥的作用3.探究S1P/S1PR1信号通路在调控肾......
目的 针对狼疮性肾炎患者实施补肾清热毒合剂联合化学药物作为治疗方案,分析疗效和免疫功能改善效果?方法选取2017年1月至2019年7月......
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A combined genome-wide transcription analysis and DNA methylation identified genes related with path
Objectives: Lupus nephritis (LN) is one of the most devastating complications and a main cause of morbidity and mortalit......
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PO262-The balance between sera interleukin 18 and sera interleukin 18 binding protein in patients wi
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Analysis of urinary monocyte chemoattractant protein-1 levels as biomarker for lupus nephritis disea
Aim:to investigate the levels of urinary monocyte chemoattractant protein-1(uMCP-1)to monitor the disease activity and l......
NOD2 involved in the inflammatory response of lupus nephritis by activation of MAPK signaling pathwa
Objectives:In our previous study,we have found an increased expression of Nucleotide-binding oligomerization domain-cont......
Background:In this study,we investigated the mechanism underlying the effects of the mTOR protein kinase inhibitor rapam......
PO388-A new immunosuppressitive agent leflunomide in treatment of lupus nephritis:58 patients with r
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Objective:Nucleotide-binding oligomerization domain(NOD)-containing 2(NOD2)is one of NOD-like receptors(NLRs)which plays......
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Background:Lupus nephritis(LN)is oneof the most common and severe complications in Systemic lupus erythematosuspatients,......
Objective: The experience of tacrolimus(TAC)in pediatric lupus nephritis(PLN)is very limited and this study aims to inve......
PO030-Incidence and significance of anticardiolipin antibodies in Chinese patients with lupus nephri
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Effects of methylprednisolone on apoptosis and expression of interleukin-1 β-converting enzyme in th
Objective To investigate the effects of methylprednisolone (MPS) on apoptesis and expression of interleukin-1 β-converti......
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Dysregulation of apoptosis: a possible mechanism leading to chronic progressive renal histological c
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Mizoribine versus mycophenolate mofetil or intravenous cyclophosphamide for induction treatment of a
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目的探究增殖性狼疮肾炎(proliferative lupus nephritis,PLN)患者血红蛋白(hemoglobin,Hb)与肾功能进展之间的关系。方法回顾性分析2010......
Patients with systemic lupus erythematosus(SLE)are found to be accompanied with innate immunity dysregulation includ......
目的提高临床对SSc合并高血压、肾功能不全的鉴别诊断水平。方法报道1例SSc合并高血压、肾功能不全患者的临床特点及诊治经过,并进......
系统性红斑狼疮(SLE)是一种累及多系统、多器官的自身免疫性全身性血管炎疾病。狼疮性肾炎(LN)是儿童SLE最常见、最严重的并发症,是......
目的探讨高迁移率族蛋白1(HMGB1)致红斑性狼疮肾损害的作用机制与Toll样受体4(Toll-like receptor4,TLR4)表达的相关性。方法ELISA检测1......
目的:通过对狼疮性肾炎(LN)风湿证与肾病理相关性研究,阐明风湿证与肾病理的关系,为风湿证微观辨证提供客观化指标以指导临床辨证与治......
目的 探讨白细胞介素13(IL-13)基因在原发性非IgA系膜增生性肾炎(MsPGN)、原发性局灶节段性肾小球硬化症(FSGS)和狼疮肾炎(LN)患者肾组织的......
Human epididymis protein 4: a novel biomarker for lupus nephritis and chronic kidney disease in syst
Objective: To investigate whether serum human epididymis protein 4 (HE4) could constitute a potential novel and usef......
A Pilot Study of the Therapeutic Efficacy and Mechanism of Artesunate in the MRL/lpr Murine Model of
Recent evidence indicates that artesunate has immunomodulatory properties that might be useful for treating autoimmune d......
目的:在运用化学法建立小鼠狼疮样肾炎模型并对其进行生物学鉴定的基础上,探讨B7-1人-鼠嵌合抗体阻断B7/D28信号通路对小鼠狼疮样......
目的 探讨肾脏病理检查在非典型狼疮肾炎(LN)诊断中的意义.方法 对28例非典型LN患者的临床和病理资料进行回顾性分析.结果 28例患......
在机体正常的免疫系统中,Th1和Th2型细胞因子通常维持动态平衡的状态,保持机体正常的免疫功能。研究表明,狼疮性肾炎( LN)患者体内普遍......
目的探讨狼疮性肾炎患者医院感染临床与病理特征,以提高临床诊治水平。方法选取2010年4月-2013年4月135例狼疮性肾炎患者为研究对......
目的分析狼疮性肾炎(LN)治疗过程中并发感染的临床特点和流行病学特征。方法回顾性分析189例LN首次确诊患者,随访1年感染的发生率、感......
系统性红斑狼疮(SLE)是一种可累及全身各脏器的自身免疫性疾病,狼疮性肾炎(LN)是SLE最常见且较严重的并发症,LN的诊治与SLE预后严密相关......
目的探讨狼疮性肾炎(LN)患者血清干细胞因子(SCF)水平及其与疾病活动度的相关性。方法选择2014年3月至2016年9月经肾活检确诊的60例住......
Objective:To observe the intervention influence and effect of simvastatin on the expression of interleukin17(LI17), high......
目的 观察环磷酰胺冲击联合来氟米特治疗难治性狼疮肾病(RLN)的效果.方法 选择确诊为RLN的患者36例,将环磷酰胺冲击联合来氟米特治......
目的:观察静脉注射中等剂量丙种球蛋白(IVIG)治疗狼疮性肾炎并细菌感染的临床效果及副反应。方法:27例病人为2010年~2013年我院住院病......
目的 探讨间歇小剂量环磷酰胺(CTX)治疗狼疮肾炎(LN)慢性肾功能不全的有效性及安全性.方法 给予12例LN慢性肾功能不全氮质血症期患......
目的 分析溶血尿毒症综合征(HUS)病因和临床特点,探讨改善预后的方法.方法 收集我科1998年7月至2004年12月20例HUS患者的临床资料,......
目的 探讨系统性红斑狼疮(SLE)并肺动脉高压(PAH)患者的临床特点、发病机制以及诊治方法.提高对该病的认识.方法 选取本院近5年住......
目的 探讨并发神经精神狼疮(NPSLE)的狼疮肾炎(LN)患者的生存率及其影响因素.方法 收集78例并发NPSLE的LN患者的临床及实验室资料,......