SILYMARIN相关论文
目的 探讨水飞蓟素(silymarin)对老年非酒精性脂肪肝(NAFLD)大鼠肝细胞增殖的影响及机制。方法 45只老年SD大鼠随机分为control组、NAF......
目的探究水飞蓟素(Silymarin)影响非酒精性脂肪性肝炎(NASH)病变进展的机制。方法1、溶剂、(PA+LPS)、(PA+LPS+Silymarin)三种方式干预人肝......
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Silybum marianum was a crop with medicinal value and ornamental value which effective components was silymarin.In this a......
Objective: To find out whether silymarin could affect the mRNA and protein levels of CYP3A4,CYP2C9, CYP2C19, CYP2D6 and ......
A novel supplement with yeast β-glucan,prebiotic,minerals and Silybum marianum synergistically modul
Objective:To evaluate the synergic effects of a novel oral supplement formulation,containing prebiotics,yeast β-glucans......
Silybum marianum(L.)Gaertn is an economic crops which contains ornamental and medicinal value.Because of it was able......
Silymarin-laden PVP-PEG polymeric composite for enhanced aqueous solubility and dissolution rate: Pr
The aim of this work was to develop, optimize and characterize a silymarin-laden polyvinylpyrrolidone (PVP)-polyethylene......
Investigation of hepatoprotective activity of Cyathea gigantea (Wall. ex. Hook.) leaves against para
Objective: To investigate the hepatoprotective activity of methanolic leaf extract of Cyatheagigantea (C. gigantea) agai......
Chronic liver disease (CLD) is an under-recognized epidemic that continues to increase in prevalence and is a major heal......
建立测定微乳中水飞蓟素含量的反相高效液相色谱法.采用ODS C18色谱柱,检测波长为288 nm,流动相为甲醇-水-冰醋酸(42:58:0.5,v/v/v......
纳米科学和纳米技术在纳米药物传递系统中具有很大的潜力.水飞蓟素纳米药物传递系统的研究和开发将改善其水溶性和脂溶性,并提高生......
Background: Abundant experimental evidence indicates overproduction of angiotensin Ⅱ in the injured liver, and a role i......
,Proliposomes for oral delivery of dehydrosilymarin: preparation and evaluation in vitro and in vivo
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Silymarin Attenuates Hepatic and Pancreatic Redox Imbalance Independent of Glycemic Regulation in th
Objective To evaluate the efficiency of silymarin (SMN) in modulating metabolic parameters and redox status in rats with......
Quantifying cardinal temperatures and thermal time required for germination of Silybum marianum seed
The response of seed germination to environmental factors can be estimated by nonlinear regression. The present study wa......
The Potential of Duck Hepatitis Virus (DHV-1) Stimulating the Body Weight Gain and the Effects of Si
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
水飞蓟素作为传统的肝脏疾病辅助治疗药物已被证实具有显著的抗氧化、抗炎的药理作用.介绍了水飞蓟素调整肝脏功能及拮抗纤维化、......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Objective To develop a highly effective HPLC method for standardization of silymarin and for characterization of minor c......
目的 观察小柴胡汤和水飞蓟素联用治疗慢性乙型肝炎肝纤维化的临床疗效.方法 90例慢性乙型肝炎肝纤维化患者随机分为两组,治疗组50......
The kinetic mechanism for the preparation of silymarin from milk thistle seeds was studied during the microwave-assisted......
The Potential of Duck Hepatitis Virus (DHV-1) Stimulating the Body Weight Gain and the Effects of Si
To evaluate the effects of duck hepatitis virus-1 (DHV-1) on the body weight gain in duck and the effects of silymarin o......
目的 观察水飞蓟素联合复方甘草酸苷治疗妊娠合并慢性乙型肝炎的疗效.方法 将105例妊娠合并慢性乙型肝炎患者完全随机分为研究组(5......
AIM: Silymarin is a potent antioxidant, antiinflammatory and anti-fibrogenic agent in the liver, which is mediated by al......
水飞蓟素是从菊科草本植物水飞蓟果实中提取出来的活性成分,具有抗氧化应激、促进蛋白合成和细胞再生的作用,是治疗各种类型肝脏疾......
Objectives To study the carbon tetrachloride-induced hepatoprotective activity in cow urine. Methods Effect of cow urine......
目的 探讨水飞蓟素诱导高转移表型肺癌细胞系Anip973细胞凋亡的分子机制.方法 采用四甲基偶氮唑蓝(MTT)比色法、倒置显微镜和电子......
目的:研究水飞蓟素对人正常肝细胞(Chang细胞株)的保护作用,尤其是其抗氧化活性和对细胞抗凋亡的保护作用。方法:采用400μmol/L H2O2......
草药的产品逐渐地被使用,主要在长期的肝疾病。牛奶蓟, Silymarin 和 silybin 的摘录,是规定天赋加重的大多数与不同指示,但是没有权威......
随着水飞蓟制剂循证医学证据的积累,水飞蓟制剂已被多部肝病诊疗指南列为抗炎保肝治疗药物。但限于篇幅,上述指南均未就水飞蓟制剂......
目的研究水飞蓟素对大鼠非酒精性脂肪性肝炎的治疗作用及部分机制研究。方法将30只大鼠随机分为3组(正常对照组、病理模型组、水飞......
目的研究水飞蓟素(SIL)、己酮可可碱(PTX)以及两者联合应用的抗纤维化疗效。方法雄性SD大鼠100只,随机分为5组,每组20只,分别为假手术对照......
目的:探讨水飞蓟素(SIL)对同型半胱氨酸(HCY)诱导的人脐静脉内皮细胞(HUVECs)凋亡的抑制作用及其作用机制。方法:采用MTT及LDH检测细胞活性......
目的 分别以水飞蓟壳和水飞蓟粕为原料,进行水飞蓟素及水飞蓟宾提取效果的比较研究,以探讨水飞蓟壳仁分离的必要性,并为制药工业中......
为评估饲料中添加水飞蓟素对吉富罗非鱼生长性能、肝脏脂肪代谢酶和抗氧化能力的影响,分别在5组等氮等能的吉富罗非鱼饲料中添加不......
目的 制备水飞蓟素固体分散体,加快药物的溶出,并进行特征考察.方法 以聚乙二醇6000(PEG 6000)为材料,采用熔融法将难溶性药物水飞......
30例单纯性高脂血症患者口服水飞蓟素片进行治疗4周后,血清总胆固醇从6.46±0.78mmol/L下降到5.08±1.06mmol/L,停药2月复查为4.99±0.97mmol/L,血清甘油三酯从1.59±0.43mmol/L下降......
The Potential of Duck Hepatitis Virus (DHV-1) Stimulating the Body Weight Gain and the Effects of Si
为了在身体重量上评估鸭肝炎 virus-1 (DHV-1 ) 的效果,在 vivo 在它上增加鸭和 silymarin 的效果, 100 只 10-d-old 鸭,男性、女性,被......
目的:建立复方水飞蓟素一丹参素滴丸溶出度测定方法。方法:采用转篮法进行溶出度试验,采用紫外分光光度法测定水飞蓟素、丹参素含量,采......
目的为了探索水飞蓟素对鸭病毒性肝炎的治疗效果。方法100只雏鸭分为5组,于11日龄接种鸭肝炎病毒。第1、2、3组腿肌接种5×104......
为了评价水飞蓟素对建鲤肝组织损伤的保护作用,探索其可能的保肝机制,本研究用含水飞蓟素(0.1、0.5和1.0 g/kg)的饲料饲喂建鲤60 d,......
建立了小鼠肝损伤模型及体内外肿瘤坏死因子诱生的方法,研究了水飞蓟宾对肝脏炎症损伤,TNF产生及其生物活性的影响。结果表明:SB在体内外均......
目的研究水飞蓟素在体外对不同乳腺癌细胞系的作用,并进一步探讨其作用机制.方法MTT实验测定水飞蓟素对乳腺癌细胞系MCF-7和SK-BR-......
AIM: Silymarin is a potent antioxidant, antiinflammatory and anti-fibrogenic agent in the liver, which is mediated by al......
瞄准:评估 2'-p-hydroxybenzoylmussaenosidic 酸的保护的效果[negundoside (NG ) ,在 HuH-7 房间对四氯化碳(CCl4 ) 导致了毒性......