Transactivation相关论文
MOR,a target of Let-7b,promotes metastasis in tongue squamous cell carcinoma by regulating transacti
Objective Aberrant expression of μ-opioid receptor(MOR)has been reported to be involved in tumor malignancy and cancer ......
Dexmedetomidine, a sedative/anesthetic and neuroprotective drug, acts via astrocytic α2-adrenergic r
Dexmedetomidine, a sedative/anesthetic drug is associated with a lower incidence of delirium and reduced length of venti......
Paeoniflorin ameliorates ischemia by transactivation of epidermal growth factor receptor mediated by
OBJECTIVETo investigate the mechanism of Paeoniflorin (PF) in vitro to illustrate its neuroprotective effects of amelior......
Monitoring dynamic protein-protein interactions during GABAB receptor mediated IGF-1R transactivatio
Many GPCR agonists can activate receptor-tyrosine-kinases (RTKs) through transactivation, the mechanisms of which are po......
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Hydrogen sulfide-linked persulfidation of ABI4 controls ABA responses through the transactivation of
Hydrogen sulfide(H2S)is a signaling molecule that regulates plant hormone and stress responses.The phytohormone abscisic......
Effect of Calpain inhibitor I on glucocorticoid receptor-dependent degradation and its transactivati
Objective: To investigate the effect of Calpain inhibitor I on glucocorticoid receptor-dependent proteasomal degradation......
Lysophosphatidic acid transactivates both c-Met and epidermal growth factor receptor, and induces cy
AIM: To examine whether lysophosphatidic acid (LPA)induces phosphorylation of c-Met and epidermal growth factor receptor......
Study of transactivating effect of pre-S2 protein of hepatitis B virus and cloning of genes transact
AIM: To investigate the transactivating effect of pre-S2 protein of hepatitis B virus (HBV) and construct a subtractive ......
目的 研究双剪接型2.2 kb乙型肝炎病毒(HBV)剪接变异体特异性蛋白TPds对病毒自身调控序列的影响.方法 PCR扩增6种HBV启动子/增强子......
Identiifcation of genes upregulated by recombinant inter feron-alpha in HepG2 cells by suppressive s
BACKGROUND:Interferon-alpha (IFN-α) is an important cytokine with multiple functions, but the target genes transactivat......
,Adenosine A1 receptor-mediated transactivation of the EGF receptor produces a neuroprotective effec
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Vitamin D3 (VD3) is a multifunctional nutrient which can be either synthesized or absorbed from the diet.It plays a pivo......
,Identification of Nuclear Factor-κB Responsive Element within the Neuronal Nitric Oxide Synthase Ex
Transcriptional regulation of the neuronal nitric oxide synthase gene (nNOS) is particularly complex as 12 distinct tran......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Interaction of hepatitis B virus with tumor suppressor gene p53: its significance and biological fun
The mechanism of the interaction of hepatitis B virus (HBV) with tumor suppressor p53 and its role in the hepatocarcinog......
Study of transactivating effect of pre-S2 protein of hepatitis B virus and cloning of genes transact
AIM: To investigate the transactivating effect of pre-S2 protein of hepatitis B virus (HBV) and construct a subtractive ......
核转录因子PPARγ与多种重大的疾病有密切关系 ,是近年来基础研究的热点及重要药物筛选靶点 .作者将一个表达PPARγ1全蛋白的重组......
以前的研究发现：ＨＢＶ Ｘ蛋白能与肿瘤抑制基因ｐ５３蛋白结合，在原发性肝癌的发生中具有重要意义。为进一步探讨二者之间的关系，经过计算机比较分......
By using molccular doning technique,the E2 gene of human papillomavirus type 16 wasexpressed in E.coli.The 3.2 kb fragme......
为研究双剪接型2．2kb乙型肝炎病毒（HBV）基因组剪接变异体特异性新蛋白-yTPds的功能，以酵母双杂交系统的诱饵质粒pGBKT7克隆yTPds基因并......
目的探讨双丁酰环腺甘酸（dBcAMP）诱导星形胶质细胞形态变化的信号传导通路。方法原代培养星形胶质细胞,采用免疫细胞化学技术检测dBc......
Identification of genes upregulated by recombinant interferon-alpha in HepG2 cells by suppressive su
BACKGROUND:Interferon-alpha(IFN-α)is an important cytokine with multiple functions,but the target genes transactivated ......
人巨细胞病毒（ＨＣＭＶ）是一种重要的病毒，属于疱疹病毒科，在普通人群中的感染率为８０％以上，对于某些特殊地区和人群，其感染率可高达１００％。人群感染ＨＣＭＶ后，通常......
以乙型肝炎病毒(HBV)X基因序列的异质性表现来探讨HBV准种在慢性感染者中的存在状态.以中国株HBV基因序列为依据,设计特异性多聚酶......
目的克隆乙型肝炎病毒(HBV)X蛋白反式激活新型靶基因.方法以HBV X蛋白表达质粒pcDNA3J(-)-X转染HepG2细胞,以空载体pcDNA3.1(-)为......
应用抑制性消减杂技术构建丙型肝炎病毒(HCV)核心蛋白反式激活基因差异表达的cDNA消减文库,克隆HCV核心蛋白反式激活相关基因.以HC......
应用抑制性消减杂交技术构建丙型肝炎病毒非结构蛋白5A(HCV NS5A)反式激活基因差异表达的cDNA消减文库,克隆HCV NS5A蛋白反式激活......
目的筛选、克隆乙型肝炎病毒(HBV)X蛋白(HBxAg)反式激活基因XTP4转染肝癌细胞后的反式调节基因,探索XTP4基因表达对肝细胞基因表达......
目的 筛选并克隆丙型肝炎病毒(HCV)非结构蛋白5A(NS5A)反式激活新型靶基因。方法 以HCV NSSA表达质粒pcDNA3．1(-)-NSSA转染HepG2细......
目的筛选并克隆乙型肝炎病毒X蛋白(HBxAg)反式激活新型靶基因.方法以HBxAg表达质粒pcDNA3.1(-)-X转染HepG2细胞,以空载体pcDNA3.1(......
目的探讨乙型肝炎病毒(HBV)X蛋白(HBV-X蛋白)对S100钙结合蛋白A11(calgizzarin S100A11)启动子转录的激活作用.方法以解放军第302......
采用HIV—LTR—Luc稳定细胞株分析其荧光素酶活性，研究Prostratin活化潜伏的艾滋病毒的分子机制．实验结果表明：随药物浓度升高和处理......
目的:应用抑制性消减杂交(SSH)技术及生物信息学(bioinformatics)技术筛选并克隆乙型肝炎病毒(HBV)前-S1蛋白(pre-S1)反式激活新型......
ＨＨＶ－６在体外可以激活ＨＩＶ ＬＴＲ引导的基因表达＾［１］，其基因组中一基因片段Ｂ７０１已被证明与这种激活作用有关＾［２］。Ｂ７０１编码１４３个氨基酸的蛋白质，可与ＨＨＶ－６基因组中其它基因片......
采用RT-PCR技术克隆了大鼠肌肉LIM蛋白（MLP）640bp的全长cDNA序列，以此cDNA为探针进行的Northern印迹表明，MLP于C2C12细胞在分化的第3d......
A Toxicological Assessment of Endocrine Disrupting Chemicals Found in the BMW (Border, Midland and W
A battery of tests was established to determine the oestrogenic, mutagenic and genotoxic potential of two categories of ......
BICP0在病毒生活周期中具有重要功能,参与对病毒以及宿主的许多启动子的激活.BHV-1超感染所引发的BIV基因表达水平的提高即与该蛋......
目的:应用抑制性消减杂交(SSH)技术构建新基因丙型肝炎病毒F蛋白结合蛋白2(HCVFBP2)反式激活基因差异表达的cDNA消减文库,克隆HCVF......
