WNTsignaling相关论文
Subchondral bone sclerosis during late osteoarthritis is mediated by loading-induced decrease in Scl
Objective: Osteoarthritis(OA)is not only a cartilage disease but also accompanied by pathologic changes in bone beneath ......
The E3 ligase RNF185 negatively regulates osteogenic differentiation by targeting Dvl2 for degradati
Osteoblast plays a pivotal role in bone metabolism and bone remodeling by mediating bone formation and regulating the ac......
Nucleus-accumulated RASSF8 promote colorectal carcinoma progression via activating Wnt signaling thr
Objective Colorectal carcinoma(CRC)is the third most commonly diagnosed cancer in males and the second in females in the......
Objective Wnt signaling,activated by secreted wnt ligands,is one of the fundamental mechanisms in development and homeos......
Aim: To investigate the effects of MNG extracted from Cornus officinalis on neurogenesis and Wnt signaling after focal c......
Wnt/β-catenin signaling is essential for embryogenesis and tissue homeostasis,which has been highly conserved through e......
Esophageal cancer is one of the most common malignancies worldwide.DACT2 is frequently methylated in human lung, hepatic......
Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 sign
Activation of Wnt/β-catenin signaling can enhance mTORC1 signaling in cancer cells.The low density lipoprotein receptor......
Gastric cancer(GC) is one of the most common cancers with a poor prognosis worldwide.The calcium sensing receptor (CaSR)......
Decreased osteogenesis of periodontal ligament stem cells through RAGE mediated by Wntsignaling in p
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βⅡ-spectrin (SPTBN1) Suppresses Progression of Hepatocellular Carcinoma and Wnt Signaling via Regula
βⅡ-spectrin (SPTBN1) is an adapter protein for Smad3/Smad4 complex formation during TGF-β signal transduction.Forty p......
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Synergistic anticancer activity of crocodile choline and paclitaxel in human hepatocellular carcinom
Method:Cell viability was determined using the MTT assay.To investigate the apoptosis mechanism induced by crocodile......
Adult mammalian cortex has long been regarded as "non-neurogenic".Recent studies have reported cortical neurogenesis......
Cenani-Lenz syndrome is caused by a novel missense mutation in LRP4 that required for limb and kidne
Cenani-Lenz syndactyly syndrome (CLS) is an autosomal recessive skeletal disorder that results in malformation of th......
Neural progenitor cells (NPCs) are sequentially specified into neurons and glia during the development of central ne......
Folate metabolism is central to biosynthesis,redox processing and transfer of one-carbon units.Folate supplementation is......
Dvl（Dishevelled）是Wnt信号通路传递的核心分子,无论内源的还是过表达的Dvl在细胞体内都能因自聚而形成puncta.研究已报道,Dvl主要通......
The canonical Wnt/β-catenin pathway is a highly conserved signaling cascade that plays critical roles during embryogene......
1 Wnt/β-catenin signalinThis signaling pathway is known to play key roles during development and in maintaining homeost......
Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointe
AIM:To clarify alterations of Dickkopfs (Dkks) and Kremen2 (Krm2) in gastrointestinal cancer.METHODS:We investigated the......
miR-199b-5p enhances the proliferation of medullary thymic epithelial cells via regulating Wnt signa
Thymic epithelial cells (TECs) are essential regulators of T-cell development and selection.miRNAs play critical roles i......
Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation
Heart regeneration occurs by dedifferentiation and proliferation of pre-existing cardiomyocytes (CMs).However,the signal......
