phosphodiesterase-4(PDE4)相关论文
Roflupram, a PDE4 inhibitor, recues cognitive dysfunction in APP/PS1 transgenic mice via cAMP/PKA/CR
Background: So far,no PDE4 inhibitors in Alzheimers disease has been approved for application in the clinic due to sever......
S2A-5 Targeting PDE4 for Alzheimer’s Disease and Alcoholism:An implication in Alcohol-Related Dement
Background:Phosphodiesterase 4(PDE4),one of the 11 PDE enzyme families that hydrolyze cyclic nucleotides,is critical for......
Peripheral nerve injury downregulates connexin43(Cx43)expression in spinal astrocytes.Therefore,restoration of spinal as......