Objectove Erythropoietin (Epo) plays a crucial role in the formation and maturation of erythroeytes and is produced primarily by peritubular cells in the renal cortex.Previous studies suggest that renal sympathetic nerve activity (RSNA) may influence Epo regulation.Catheter-based renal denervation (RDN) has been shown to reduce renal noradrenaline spillover and blood presstre in patients with resistant hypertension.We therefore aimed to investigate whether RDN influences Epo levels.