疏水相互作用强度对多肽链自组装结构的影响

来源 :中国化学会第三届全国生物物理化学会议暨国际华人生物物理化学发展论坛 | 被引量 : 0次 | 上传用户：zhoulei1964

【摘要】

：

高度有序的多肽链纳米结构的形成是分子间各种相互作用协同的结果.我们采用粗化模型和蒙特卡罗模拟方法研究了多肽链侧链间的疏水相互作用强度对其自组装结构的影响.发现随着疏水相互作用强度和温度的变化,多肽链可以形成各种自组装结构,展现出丰富的相行为.这表明多肽链自组装结构和形貌可以通过改变疏水作用强度和温度来调控.我们的模拟结果可以为设计基于多肽链纤维结构的新型纳米生物材料提供理论依据.

【机构】

：

华南理工大学材料科学与工程学院,510641,广州

【出处】

：

中国化学会第三届全国生物物理化学会议暨国际华人生物物理化学发展论坛

【发表日期】

：

2014年5期

【关键词】

：

多肽链自组装蒙特卡罗模拟疏水相互作用 β折叠

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疏水相互作用强度对多肽链自组装结构的影响

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