Bioequivalence of micronised fenofibrate capsual in healthy volunteers

来源 :第二届“定量药理与新药评价”国际学术会议 | 被引量 : 0次 | 上传用户:odeartiger
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  AIM To study the pharmacokinetics and bioequivalence of domestic and imported micronised fenofibrate capsual in healthy volunteers.METHODS The study was designed in 20 healthy volunteers according a two-treatment , two-period , two-sequence randomized cross-over trial.Plasma concentrations were determined by HPLC method, ketoprofen was used as the internal standard.The pharmacokinetics parameters were calculated statistically to evaluate the bioequivalence between the tow preparations by BAPP2.2 software.
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