Histone demethylase JMJD3 is a new co activator of hypoxia-inducible factor 2α

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户:tvxq905
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  The histone H3 Lys 27 (H3K27) demethylase JMJD3 has been shown to play important roles in transcriptional regulation and cell differentiation.
其他文献
  The cyclin-dependent kinase inhibitor 1A (CDKN1A), p21/Cipl, is a vital cell cycle regulator, dysregulation of which has been associated with a large number
会议
  Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) has emerged as a cancer therapeutic agent because of its capability of inducing apoptosis i
会议
  As an alternative to genetic changes, epigenetic changes contribute to the aberrant activation of oncogenic signaling in human cancers.
会议
  硫化氢(H2S)作为一种新型气体信号分子参与动植物细胞的多种生物学过程,尤其是参与植物非生物胁迫应答,如干旱、低温、高盐、热激、重金属离子毒害等。水涝胁迫作为常见
  Gsdmina3对于小鼠皮肤上皮细胞以及毛囊细胞的增殖、分化、凋亡等生理活动有着密切关系.Frizzled作为Wnt/β-catenin信号通路的受体会参与毛囊的形态建成以及毛囊周期的
  Glutaminase C (GAC) is a key metabolic enzyme and play an important role in the glutamine metabolism which was shown to be essential for some cancer cell gr
会议
The p2 l-activated kinase 5 (PAK5) is overexpressed in advanced cancer and the transcription factor E47 is a direct repressor of E-cadherin and inducer of epith
会议
  Small cell lung cancer (SCLC) has a strong predilection for brain metastasis.However, the molecular basis is poorly known.Here,we found that the elevated se
会议
  Epithelial-mesenchymal transition (EMT) is a key process in tumor metastatic cascade that is characterized by the loss of cell-cell junctions, resulting in
会议
  Apigenin(4',5,7,-trihydroxyflavone) is a common non-mutagenic plant flavonoid widely distributed in vegetables and fruits that has a broad spectrum of anti-
会议