Readout circuit is designed for a special retina-like CMOS sensor.To realize the pixels timing drive and readout of the sensor,the Alteras Cyclone II FPGA is used as a control chip.The voltage of sensor is supported by a voltage chip initialized by SPI with AVR MCU system.The analog image signal outputted by the sensor is converted to digital image data by 12-bits A/D converter ADS807 and the digital data is memorized in the SRAM.Using the Camera-link image grabber,the data stored in SRAM is transformed to image shown on PC.Experimental results show the circuit works well on retina-like CMOS timing drive and image readout and images can be displayed properly on the PC.