【摘 要】
:
Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases.The enhanced nitrative stress plays an important role in homocysteine-induced endothelial dysfunction.Previous studies ha
【机 构】
:
首都医科大学基础医学院生理学与病理生理学系 北京 100069
【出 处】
:
第九届海峡两岸心血管科学研讨会暨首届台湾南部国际心脑血管科学研讨会
论文部分内容阅读
Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases.The enhanced nitrative stress plays an important role in homocysteine-induced endothelial dysfunction.Previous studies have showed that phytoestrogen α-zearalanol could alleviate the impairment of vascular endothelium in ovariectomized hyperhomocysteinemia rats; however, the underlying mechanism remains to be clarified.
其他文献
Vascular endothelial growth factor (VEGF), in addition to its essential role in the processes of vascularization and angiogenesis, exerts direct effects on neural cells in the central nervous system.T
Purpose: Recent studies have implicated the human cytomegalovirus (HCMV) as a possible pathogen for causing hypertension.We aimed to study the association between HCMV infection and hypertension in th
Background-5 adenosine monophosphate-activated protein kinase (AMPK) has been shown to interact with peroxisome proliferator-activated receptor delta (PPARδ) to induce gene expression synergistically
Background: Association between vitamin D insufficiency and hyperuricemia has not been reported so far.We aimed to study the association of vitamin D insufficiency with elevated serum uric acid among
目的:缺氧诱导的冠状动脉痉挛是导致心绞痛发生的一个重要原因.研究发现缺氧可以激活PI3K/Akt信号通路该通路在血管平滑肌的张力调节中起重要做用.本研究试图明确PI3K/Akt信号通路是否介导了缺氧诱导的猪冠状动脉痉挛,以及临床上常用的心绞痛治疗药物硝酸甘油是否可以通过调节PI3K/Akt从而改善冠状动脉痉挛.
内皮祖细胞(endothelial progenitor cells,EPCs)在血管损伤后内膜的修复和缺血性疾病的血管新生中超重要作用.流体切应力(shear stress,SS)是调节内皮祖细胞向内皮细胞(endothelial cells,ECs)分化的重要因素.在切应力诱导EPCs分化的研究报道中,目前尚未涉及microRNAs (miRNAs)的调节作用.本研究探讨了microRNA-3
Palmitic acid (PA), one of saturated free fatty acids impairs the cardiovascular function manifested by vascular inflammation, vascular cell apoptosis and over-production of reactive oxygen species (R
The Chinese medicine Astragali radix has been used to treat stroke sequelae for a long time.A few reports indicate that Astragali Radix extract or its purified components can affect brain function, pr
Studies have indicated that both ginsenoside Rbl and ghrelin could prevent homocysteine (Hcy)-induced endothelial dysfunction through eNOS/NO mechanism.Our study showed that endogenous ghrelin mediate
Endothelial progenitor cells (EPCs) play an important role in postnatal neovascularization and re-endothelialization in response to tissue ischemia and endothelial injury.It is reported that the circu