Regulation of Navl.7 by microRNA30b in dorsal root ganglion neurons following the sciatic nerve inju

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The tetrodotoxin-sensitive voltage-gated sodium channel isoform Navl.7 encoded by SCN9A and predominantly expressed in dorsal root ganglion (DRG) pain-sensing neurons plays a critical role in nociception.MicroRNAs are highly conserved short non-coding RNA targeting mRNA 3-untranslated region (3UTR) for cleavage or translation inhibition.
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