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Objective: We conducted a retrospective study to evaluate the role of prophylactic cranial irradiation (PCI) on patients with surgically resected small cell lung cancer(SCLC).Method: The records of completely resectable patients who were diagnosed with SCLC and definited TNM stage on the basis of histological studies between January 2003 and December 2009 were reviewed.According to the therapy modality including PCI or not, patients were allocated in PCI group and non-PCI group.