• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Growth inhibition and apoptosis induction effects on human tumor cell lines by actinomycin D and Its

Growth inhibition and apoptosis induction effects on human tumor cell lines by actinomycin D and Its

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：dh482600
【摘 要】
：
Aims: As an important natural product resource, the diversity and chemical complexity of marine microorganism are treasury for development of new antitumor drugs.In the present study, growth inhibitor
【作 者】
：
Sheng-qian YANG Yu YAN Huan-li XU Yang-yang HE Yong-jie LI Li LI Guan-hua DU 
【机 构】
：
Beijing Key Laboratory of Drug Targets Identification and Drug Screening,Institute of Materia Medica
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
actinomycin D cancer growth inhibition apoptosis Streptomyces parvus 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Aims: As an important natural product resource, the diversity and chemical complexity of marine microorganism are treasury for development of new antitumor drugs.In the present study, growth inhibitory and pro-apoptosis effects of actinomycin D (Act D) and its analog (DL1106-2) from Streptomyces parvus REL-3 were investigated in vitro.
其他文献
The effects of extracts from Astragalus membranaceue Bge(ABM) on HepG2 cell
Aim: To observe the effect of extracts from Astragalus membranaceue Bge (AMB) on HepG2 cell and its molecular mechanism.Methods: HepG2 cells were cultured in 2 groups: control group and AMB group; MTT
会议
Astragalus membranaceue BgeHepG2Bcl-x1p53
Investigation of protective effect of Luobuma (Apocynum venetum) extract and its metabolites against
Aims: According to pervious publications, Luobuma (Apocynum venetum) extract showed protective effect for liver damage in in vitro and in vivo models, and the bioactive compounds were considered to be
会议
Apocynum venetumHepG2 cellsethanolparacetamolt-BHP
Caffeic acid 3,4-dlhydroxyphenethyl ester arrests colorectal cancer cells growth by upregulating pho
Aims: Caffeic acid 3,4-dihydroxyphenethyl ester (CADPE) has been reported to possess a broad spectrum of antitumor activity; however, its antitumor mechanism is not well understood.In this study, we i
会议
CADPEhuman colon cancer cellscell cycleCdc25A-Cdk2/4-Rb pathwayp38 MAPK
Tangeretin enhances the therapeutic effect of 5-Fu against colon cancer In vivo and In vitro by inhi
Aim: Tangeretin exhibits anti-proliferative, anti-invasive, anti-metastatic and antioxidant activities under several cancer models in vivo.In this study, we evaluate the effects of tangeretin alone or
会议
tangeretin5-FUcolon cancersynergistic effectmiR-21
Furanodiene induces G1 cell cycle arrest and activates the signaling molecules regulating apoptosis
Aim: This study aims to systematically investigate the effects of furanodiene (FUR), a natural terpenoid isolated from Rhizoma Curcumae, on cell viability and significant processes of tumor progressio
会议
furanodienecell cycleapoptosisautophagymetastasis
Anti-cancer effects of triterpenoids Isolated form Alismatis Rhizoma on HepG2 cells
Aim: This study aims (1) to isolate different types of compounds from Alismatis Rhizoma, a well-known traditional Chinese medicine, (2) to compare the anti-cancer activities in vitro, and (3) to study
会议
Alismatis Rhizomatriterpenoidalisol Bcancerstructure-activity relationship
Study on the purification and Identification for anti-tumor activity of DL1106 and its analogue
Aim: To get enough quantity and quality of DL1106 and its analogue to evaluate their anti-tumor activity, the fermentation conditions of marine actinomycetes REL-3 were optimized.Methods: Estimating t
会议
REL-3DL1106analogueHPLCanti-tumor
Gecko Peptides Mixture induce apoptosis in human esophageal squamous carcinoma EC109 cell line in vi
Aims: To investigate the effect of Gecko Peptides Mixture (GPM) on apoptosis of human esophageal squamous carcinoma EC109 cell line and the molecular mechanisms.Methods: EC109 cells were cultured in v
会议
gecko peptides mixturehuman esophageal squamous carcinomaapoptosisBcl-2caspa
Molecular basis of elF3a gene In therapeutic response of lung cancer patients to platinum-based chem
Drug resistance is one of the major obstacles in successful chemotherapy of lung cancers.However, the mechanism of resistance is not yet clearly understood.Recently, eIF3a that plays an important role
会议
Attenuation of tumor formation by Ardisia crispa root In murine skin carcinogenesis model
Aim: Ardisia crispa has been traditionally used to treat inflammation-related diseases.In this study, chemopreventive effect of its triterpene-and quinonerich fraction (TQRF) was investigated.Methods:
会议
Ardisia crispaskin cancerchemopreventiontriterpenequinone