Zn2+ ions are the second must abundant transition metal ions in the human body after iron and essentialcofactors in many biological processes like brain function and pathology.
The ring polymer molecular dynamics (RPMD) calculations are performed to calculate rate constants for the title reaction on the recently constructed potential energy surface based on permutation invar
Calcium release-activated calcium (CRAC) channels are integral proteins of the plasma membrane,and play a central role in cellular signaling by generating a sustained influx of calcium following its d