论文部分内容阅读
Relighting Photosensitizers by Synergistic Integration of Albumin and Perfluocarbon for Enhanced Pho
【机 构】
：
State Key Laboratory of Pharmaceutical Biotechnology,Medical School of Nanjing University,Nanjing 21
【出 处】
：
2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年
【发表日期】
：
2016年4期
其他文献
Excipient has been widely used in commercial protein drugs,while its selection for a particular protein formulation is generally based on trial-and-error and sometimes can not achieve the desired effe
large number of lead compounds have low solubility in water,which greatly hinders their clinical application.Recently,nanosuspensions have been considered as a promising strategy in the delivery of wa
Coordination-driven Assembly of Catechol-modified Chitosan for Kidney-specific Delivery of Salvianol
Kidney-specific delivery is critically important for treatment of renal fibrosis with drugs such as Salvianolic acid B(Sal B).[1,2] In this study,we report a kidney-specific nanocomplex formed by coor
Study on the cell penetrating peptide targeting to brain(PTB)based on RVG29R9 and PTB modified lipos
It was reported that the conjugate compound of nona-arginine(R9)and 29 peptides from rabies virus glycoprotein(RVG),a substrate of N-acetylcholine receptor,had delivered siRNA into the brain tissue ef
Cyclopamine regulatingthe tumor microenvironment enhanced photo-thermotherapy of erythrocytemembrane
Due to the rich stroma content and poor blood perfusion,pancreatic ductal adenocarcinoma(PDA)is a tough cancer that can hardly be effectively treated by chemotherapeutic drugs.In the present study,cyc
会议
A gene delivery system containing nuclear localization signal:increased nucleus import and transfect
会议
PEGylation facilitates oral absorption of intact lipid-based nanoparticlesby slowing down in vivo li
PEGylation has been widely applied to improve the oral absorption of proteins and peptides as well as drug delivery systems.However,the exact role of PEGylation in oral delivery remains unclear.
Biodegradable cross-linked micelles enhance nuclear drug delivery and cancer therapeutic efficacy by
会议
Targeting-penetration core-shell functional polymeric micelles cross the BBB for glioblastoma therap
Angiopep-2 was used as a dual-targeting ligand based on its high affinity to low density lipoprotein receptor-related proteins 1(LRP1),which is over-expressed in both BBB and glioma cells.
Enhanced cellular internalization and on-demand intracellular release of doxorubicin by stepwise pH/
The efficient delivery of anti-tumor agents to tumor sites faces numerous obstacles,such as poor cellular uptake and slow intracellular drug release.In this regard,smart NPs that respond to the unique