Ex Vivo Expanded Human Peripheral Blood Vδ1 γδT Cells Exhibit Potent Colon Cancer Killing Properties

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：x28221181

【摘要】

：

Purpose: Vγ9Vδ2 γδT (Vδ2 T) cells-based adoptive immunotherapy for most solid tumors has limited success.This study aims to determine whether Vδ1 γδT (Vδ1 T) cells can be used as an effective adoptive

【作者】

：

Dang Wu Pin Wu Xianguo Wu Jun Ye Zhen Wang Shuai Zhao Chao Ni Guoming Hu Jinghong Xu Yuehua Han Ting Zhang Fuming Qiu Jun Yan Jian Huang

【机构】

：

The Second Affiliated Hospital of Zhejiang University School of Medicine

【出处】

：

中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年10期

【关键词】

：

adoptive cellular immunotherapy cytotoxicity human colon cancer human PB Vd1 T c

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Dynamic profiles of antibody response to H7N9 infection in five patients

Background: Five human infections were caused by avian-origin influenza A (H7N9) virus in Nanchangcity during H7N9 outbreak in 2013.Objective: To understand the dynamic profiles of antibody response t

会议

H7N9 infectionAntibody responseHemagglutination inhibition assayAntiviral the

Gamma-interferon induces type Ⅰ interferon production by augmenting toll-like receptor 9 expression

研究目的 : Whether and how type Ⅰ interferon plays the role in the anti-MHV-68 effect of IFN-γ.研究方法 : We detected the expression and production of IFN-α/β by RT-qPCR and ELISA respectively, and the expres

会议

Type Ⅰ and type Ⅱ interferonMHV-68TLR9BMM

Molecular cloning, polymorphism and antigen presentation analysis of classical MHC class Ⅰ alleles i

Since the northern pig-tailed macaque (Macaca leonina) has been divided from the pig-tailed macaques group and identified as an independent species of Old World m, we previously found that PBMCs from

会议

Northern pig-tailed macaqueMHC class ⅠHIV/AIDS model

Protective Efficacy and Mechanism of Passive Immunization with Polyclonal Antibodies in a Sepsis Mod

Introduction: Staphylococcus aureus (S.aureus) is an opportunistic bacterial pathogen responsible for a diverse spectrum of human diseases.Globally, it is a leading cause of nosocomial and community a

会议

Staphylococcus aureusPassive ImmunizationPolyclonal Antibodiessepsis

The Therapeutic Effect of Pamidronate on Lethal Avian Influenza A H7N9 Virus Infected Humanized Mice

Objective: A novel avian influenza virus H7N9 infection occurred among human populations since 2013.Although the lack of sustained human-to-human transmission limited the epidemics caused by H7N9, the

会议

Vdelta2-T cellAmidronateOseltamivirHumanized mice

TLR4基因敲除对IgA肾病模型小鼠干预效果的观察

目的：建立IgA肾病野生型及TLR4基因敲除小鼠模型，观察TLR4基因敲除对IgA肾病模型小鼠血液和尿液的生化指标、肾组织病理改变、肾脏IgA沉积及骨髓IgA淋巴细胞变化的干预效果，探讨TLR4在IgA肾病过程中的作用。

会议

IgA肾病TLR4基因敲除小鼠

瑞香素体外抗肠道病毒71的作用

目的：在体外观察瑞香素抗肠道病毒71的作用效果。方法：瑞香素作用于RD细胞,CCK-8法检测其细胞毒性,并分别在病毒感染细胞的不同阶段加入不同浓度瑞香素,观察细胞病变(CPE),CCK-8法检测并计算病毒抑制率、半数有效浓度(IC50),评价瑞香素的抗病毒效果。

会议

瑞香素肠道病毒71型体外

A novel murine anti-lactoferrin monoclonal antibody activates human polymorphic mononuclear cells th

Objective: Lactoferrin (LTF) is a soluble iron-binding glycoprotein of the transferrin family mainly present in mammalian body fluids.

会议

membrane-bound lactoferrinneutrophilsTLR-4

LCP enhance chemotherapy cytotoxicity through modulation of anti-tumor immune microenvironment

Background: Galectin-3(Gal-3) is an important tumor antigen and an immune modulator functioning complicated in the process of anti-tumor immunity.

会议

Low-Molecular-Weight Citrus-Pectin(LCP)Myeloid derived suppressive cells (MDSC)

Identification of VEGFR-3 and STK4 as new targets for inflammation-related diseases

TLR-triggered uncontrolled inflammation plays key role for the induction of endotoxin shock and inflammation-associated hepatocellular carcinoma (HCC).

会议

VEGFR-3VEGF-CSTK4macrophageTLR pathwayinflammationSepsisHCC

Ex Vivo Expanded Human Peripheral Blood Vδ1 γδT Cells Exhibit Potent Colon Cancer Killing Properties

与本文相关的学术论文