【摘 要】
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Modern maize breeding process have generated enormous amount of genetic variants which may contribute to the phenotype diversity.On top of re-sequencing data of 278 maize inbred lines,we expanded the
【机 构】
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State Key Laboratory of Agrobiotechnology and National Maize Improvement Center,China Agricultural U
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Modern maize breeding process have generated enormous amount of genetic variants which may contribute to the phenotype diversity.On top of re-sequencing data of 278 maize inbred lines,we expanded the population to 778 lines with～1.5x depth on average and identified 56 million SNPs.About 30 ％of the SNPs are novel and enriched in rare SNPs.The non-syn/syn ratio is 1.09 which is comparable with the report in 278 lines,but lower than rice (1.29) and soybean (1.38).We found the ratio of non-syn/syn are 1.28,1.16 and 0.81 for SNPs with maf ＜ 0.01,0.01＜maf＜0.05 and maf ＞0.05,which indicates strong purifying selection during maize breeding.The genetic diversity are lowest in CDS regions (θπ =0.0049 and θw =0.0045),while the genetic diversity in the upstream and downstream 2kb of genes (θπ =0.0091 and θw =0.0085) are～1.4 fold higher than the whole genome level (θπ =0.0065 and θw =0.0069).
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