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目的:通过实验研究探讨五种归肺经中药麻黄、紫菀、桑白皮、鱼腥草、桔梗的止咳及抗炎作用。方法:用浓氨水致咳法、二甲苯致小鼠耳廓肿胀法。结果:麻黄、紫菀、桑白皮、鱼腥草可延长模型动物咳嗽潜伏期;紫菀、桑白皮、桔梗可减少咳嗽次数;而麻黄、桔梗、紫菀、桑白皮有不同程度的抑制二甲苯致小鼠耳廓肿胀作用。结论:麻黄、紫菀、桑白皮、鱼腥草、桔梗均具有不同程度的止咳作用,麻黄、桔梗、紫菀、桑白皮有一定的抗炎作用。
OBJECTIVE: To study the antitussive and anti-inflammatory effects of five kinds of herbs for epidermis, ephedra, mulberry white skin, Houttuynia cordata and Platycodon grandiflorum by means of experimental study. Methods: Cough method with concentrated ammonia, xylene-induced ear swelling in mice. Results: Ephedra, aster, mulberry bark and Houttuynia cordata could prolong the latent period of cough in the model animals; Aster, Morus alba and Campanulaceae could reduce the number of coughs; while Ephedra, Campanulaceae, aster and bark inhibited the xylene-induced Mouse ear swelling effect. Conclusion: Ephedra, Aster, Morus alba, Houttuynia cordata, Campanulaceae have different levels of cough suppression, ephedra, balloonflower, Aster, Morus alba have some anti-inflammatory effects.