HPLC-MS/MS法测定人血浆中多奈哌齐浓度的不确定度评定

来源 :中华医学会临床药学分会2014年全国学术会议 | 被引量 : 0次 | 上传用户:mars1998
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目的 建立HPLC-MS/MS法测定人血浆中多奈哌齐浓度的不确定度分析方法.方法 建立HPLC-MS/MS法测定含量的数学模型,分析测量不确定度的来源,量化各个测量不确定度分量,合成标准测量不确定度,给出扩展测量不确定度报告.结果 高、中、低三个浓度的扩展不确定度分别为0.084、0.138、1.323 μg·ml-1.
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