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5. The miR-23b/27b cluster balances BMP-7 and TGF-β signalings to suppress HSCs activation through down

The miR-23b/27b cluster balances BMP-7 and TGF-β signalings to suppress HSCs activation through down

来源 :第19次全国干扰素与细胞因子学术会议 | 被引量 : 0次 | 上传用户：gmwang2009

【摘 要】

：

Imbalance of the TGF-β and BMP-7 signaling pathways is a critical step in promoting hepatic stellate cell (HSC) activation during hepatic fibrogenesis.Gremlinl may contribute to impairment of the bala

【作 者】

：

Xian-Yi Zeng Yan-Qiong Zhang Xiao-Min He Lin-Yan Wan Hu Wang He-Jie Xiao Jiang-Feng Wu Chang-Bai Liu 

【机 构】

：

Medical College, China Three Gorges University, Yichang, China, 443002;Institute of Liver Diseases,

【出 处】

：

第19次全国干扰素与细胞因子学术会议

【发表日期】

：

2016年10期

【关键词】

：

Hepatic fibrosis TGF-β BMP-7 Micro RNA siRNA 

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　　Imbalance of the TGF-β and BMP-7 signaling pathways is a critical step in promoting hepatic stellate cell (HSC) activation during hepatic fibrogenesis.Gremlinl may contribute to impairment of the balance of TGF-β and BMP-7-mediated signal transduction.

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