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Algicidal microbes could effectively remove the harmful algae from the waters.In this study, we were concerned with the ecological influence of an algicide extracted from Streptomyces alboflavus RPS, which could completely lyse the Phaeocystis globosa cells within two days.In microcosms, 4 μg/mL of the microbial algicide could efficiently remove P.globosa cells without suppressing other aquatic organisms.Bioluminescent assays confirmed that the toxicity of microbial algicide at this concentration was negligible.Interestingly, the toxicity of P.globosa exudates was also significantly reduced after being treated with the algicide.