论文部分内容阅读
Through temporally and spatially modified proteins, post-translational modifications (PTMs) greatly expand the proteome diversity and play critical roles in regulating the biological processes.Identification of site-specific substrates is fundamental for understanding the molecular mechanisms and functions of PTMs, which is still a great challenge under current technique limitations.Development of computational approaches has promoted studies of PTMs, since in silico predictions and analysis could rapidly generate useful information for later experimental investigations.