Nucleic acid drug is challenging for their delivery efficiency,and cationic lipid is generally cytotoxic.In this paper,we described a novel cytimidine-based
The human Bloom syndrome gene(BLM)encodes a RecQ 3-5 DNA helicase,which is important in genomic stability by suppressing sister chromatid exchanges(SCE)duri
Although Waston-Crick base-pairing is central to DNA replication,the molecular basis of how DNA polymerases faithfully decode the chemical information on th
Our phenotypic screening of anti-cancer compounds in a library of multi-component reaction products found that a series of novel α-propiolamino-β-arylamin