论文部分内容阅读
Senescent human diploid fibroblasts (HDFs) were reported to be mostly insensitive to mitogenic stimuli.However,we found that proliferative potential of senescent HDFs was increased by lysophosphatidic acid (LPA) and adenylyl cyclase inhibitor SQ22536 (ACI).In a previous study,we found that LPA increased the cAMP level but ACI completely inhibited its elevation.