Amines are important structural motifs and intermediates for fine chemicals,pharmaceuticals,agrochemicals and natural products.Consequently,the development of general and efficient methods for the synthesis of amines is an active research topic in modern organic synthesis and medicinal chemistry.Among the various methods,the most prominent reactions are Buchwald-Hartwig coupling and Ullmann-type aminations,in which aryl halides are frequently used as electrophiles to couple with amines.