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  5. All-trans retinoic acid prevents reperfusion injury post-myocardial infartion in diabetic mice by in

All-trans retinoic acid prevents reperfusion injury post-myocardial infartion in diabetic mice by in

来源 :第十二届中国介入心脏病学大会(CIT2014) | 被引量 : 0次 | 上传用户：qtedu
【摘 要】
：
Background Previous studies have shown that All-trans-retinoic acid (ATRA) educes apoptotic preventing effect in numerous cell types by down-regulating apoptotic signals.But its utility in Ischemia-re
【作 者】
：
Zhu Zhengbin Zhao Xiaoran Zhu Jinzhou Lu Lin Zhang Fengru Shen Weifeng Zhang Ruiyan 
【机 构】
：
Department of Cardiology,Rui Jin Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai,
【出 处】
：
第十二届中国介入心脏病学大会(CIT2014)
【发表日期】
：
2014年3期
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Background Previous studies have shown that All-trans-retinoic acid (ATRA) educes apoptotic preventing effect in numerous cell types by down-regulating apoptotic signals.But its utility in Ischemia-reperfusion (I/R) injury remains unclear.Receptor of advanced glycation end products (RAGE) has been demonstrated to play a key role in I/R injury.This study was designed to reveal the effect of ATRA in preventing I/R injury in diabetic mice and its correlation with RAGE.
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