Peyronie disease (PD) is characterized as a fibrous,inelastic lesion of the tunica albuginea.It is thought to result from trauma or microtrauma to the erect penis in genetically susceptible individuals, though the mechanism of disease has not been fully elucidated.The lesion can be painful in some individuals, and can also result in erection deformities making intromission difficult or impossible.Treatment options are chosen based upon disease severity,patient preference, and surgeons training.Options include oral medications, intralesional injection therapy, plication procedures, incision and grafting, and placement of a penile prosthesis with or without manual modeling or other ancillary straightening techniques.Numerous nonsurgical treatment options have been utilized since PD was first descriptively named in 1743.