3Disease Browser A Web server for integrating 3D genome and disease-associated chromosome rearrangem

来源 :2016年第三届全国功能基因组学学术峰会 | 被引量 : 0次 | 上传用户:zhangqiang
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Chromosomal rearrangement (CR) events have been implicated in many tumor and non-tumor human diseases.CR events lead to their associated diseases by disrupting gene and protein structures.Also,they can lead to diseases through changes in chromosomal 3D structure and gene expression.
其他文献
  The kinetic participation of macrophages, especially M1 to M2 transition, is critical in the healing of myocardial infarction (MI).However, the mechanisms u
会议
Cardiovascular diseases (CVDs) caused by atherosclerosis are among the leading causes for mortality and morbidity in industrialized countries while China, as a
会议
Compilation of a minimum set of precise genetic markers with the most predictive effectiveness,multiple functions and diagnostic indications is the centre of ei
Omega 3 polyunsaturated fatty acids (ω3 PUFAs) such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are recognized as agonists of free fatty acid
会议
Pulmonary arterial hypertension (PAH) is a severe and progressive disease, which is commonly associated with chronic hypoxemia in disorders such as chronic obst
会议
Background: Failure of resolution mechanisms contribute to disease pathogenesis in non-neoplastic inflammatory diseases.Inflammation in the tumor microenvironme
会议
Over the past decade,rapid advances in genomics,proteomics and functional genomics technologies enable in-depth interrogation of cancer genomes and proteomes,an
To obtain kilobase resolution chromatin interactions at low cost remains a major challenge.We present algorithms,named CISD and CISD_loop,to precisely identify
Structural variation (SV) is an important class of genomic variations in human genomes.Until recently,a number of SV detection algorithms based on high-throughp
Genome-wide association studies (GWAS) have been widely used in genetic dissection of complex traits.However,common methods are all based on a fixed-SNP-effect