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NMR spectroscopy is an important research and clinical technology that has been widely appreciated due to its unique ability of providing accurate molecular information in a non-destructive manner (unlike e.g.mass spectrometry).Its intrinsically low sensitivity,severely has limited the investigation of mass-and volume-limited samples).1 To counter this problem, miniaturizing the NMR detection coil has become a necessity, owing to the fact that probe sensitivity is enhanced by matching the diameter of coils to the sample volume.2 Another major advantage of microcoil probes is the potential for incorporation with the rapidly emerging field of microfluidic lab-on-a-chip systems.3,4 providing a densely integrated assembly which is capable of handling microscale samples and monitoring them in continuous flow.