【摘 要】
:
Fragile X mental retardation 1 gene (FMR1) is the disease-determining gene of fragile X syndrome (FXS),which has been proved to have several splicing products,b
【机 构】
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南京军区福州总医院全军计划生育优生优育研究所,福州,350025
【出 处】
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中国生物工程学会2014年学术年会暨全国生物技术大会
论文部分内容阅读
Fragile X mental retardation 1 gene (FMR1) is the disease-determining gene of fragile X syndrome (FXS),which has been proved to have several splicing products,but the proportionality of spliced isoforms in any given tissue remains unclear.In our study,T cloning-sequencing approach was used to analyze long-chain RT-PCR products of the whole coding region from the FMR1 gene in human tissues,especially the FXS-related tissues,brain and testis.Twenty alternatively spliced products were found in 271 recombinants,including six novel ones.
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